Why does trehalose not improve autophagy in the SOD1G93A transgenic mouse model of familial ALS?

Amyotrophic lateral sclerosis is one of the major neurodegenerative diseases, causing an ascending paralysis that usually kills the patient within a few years from disease onset. The motor neurons show aggregates of proteins which in approximately 20 % of cases of the familial form contain mutated S...

Full description

Bibliographic Details
Main Author: Karlsson, Karolina
Format: H3
Language:Inglés
Swedish
Published: SLU/Dept. of Biomedical Sciences and Veterinary Public Health (until 231231) 2015
Subjects:

Similar Items: Why does trehalose not improve autophagy in the SOD1G93A transgenic mouse model of familial ALS?