Biofortified b-carotene rice improves vitamin A intake and reduces the prevalence of inadequacy among women and young children in a simulated analysis in Bangladesh, Indonesia, and the Philippines

Background: Vitamin A deficiency continues to be a major public health problem affecting developing countries where people eat mostly rice as a staple food. In Asia, rice provides up to 80% of the total daily energy intake. Objective: We used existing data sets from Bangladesh, Indonesia, and the Ph...

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Autores principales: De Moura, Fabiana F., Moursi, Mourad, Angel, Moira Donahue, Angeles-Agdeppa, Imelda, Atmarita, Atmarita, Gironella, Glen M., Muslimatun, Carriquiry, Alicia
Formato: Journal Article
Lenguaje:Inglés
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://hdl.handle.net/10568/146393
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author De Moura, Fabiana F.
Moursi, Mourad
Angel, Moira Donahue
Angeles-Agdeppa, Imelda
Atmarita, Atmarita
Gironella, Glen M.
Muslimatun
Carriquiry, Alicia
author_browse Angel, Moira Donahue
Angeles-Agdeppa, Imelda
Atmarita, Atmarita
Carriquiry, Alicia
De Moura, Fabiana F.
Gironella, Glen M.
Moursi, Mourad
Muslimatun
author_facet De Moura, Fabiana F.
Moursi, Mourad
Angel, Moira Donahue
Angeles-Agdeppa, Imelda
Atmarita, Atmarita
Gironella, Glen M.
Muslimatun
Carriquiry, Alicia
author_sort De Moura, Fabiana F.
collection Repository of Agricultural Research Outputs (CGSpace)
description Background: Vitamin A deficiency continues to be a major public health problem affecting developing countries where people eat mostly rice as a staple food. In Asia, rice provides up to 80% of the total daily energy intake. Objective: We used existing data sets from Bangladesh, Indonesia, and the Philippines, where dietary intakes have been quantified at the individual level to 1) determine the rice and vitamin A intake in nonpregnant, nonlactating women of reproductive age and in nonbreastfed children 1–3 y old and 2) simulate the amount of change that could be achieved in the prevalence of inadequate intake of vitamin A if rice biofortified with β-carotene were consumed instead of the rice consumed at present. Design: We considered a range of 4–20 parts per million (ppm) of β-carotene content and 10–70% substitution levels for the biofortified rice. Software was used to estimate usual rice and vitamin A intake for the simulation analyses. Results: In an analysis by country, the substitution of biofortified rice for white rice in the optimistic scenario (20 ppm and 70% substitution) decreased the prevalence of vitamin A inadequacy from baseline 78% in women and 71% in children in Bangladesh. In Indonesia and the Philippines, the prevalence of inadequacy fell by 55–60% in women and dropped by nearly 30% in children from baseline. Conclusions: The results of the simulation analysis were striking in that even low substitution levels and modest increases in the β-carotene of rice produced a meaningful decrease in the prevalence of inadequate intake of vitamin A. Increasing the substitution levels had a greater impact than increasing the β-carotene content by >12 ppm.
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spelling CGSpace1463932025-01-24T08:54:26Z Biofortified b-carotene rice improves vitamin A intake and reduces the prevalence of inadequacy among women and young children in a simulated analysis in Bangladesh, Indonesia, and the Philippines De Moura, Fabiana F. Moursi, Mourad Angel, Moira Donahue Angeles-Agdeppa, Imelda Atmarita, Atmarita Gironella, Glen M. Muslimatun Carriquiry, Alicia carotenoids gender biofortification simulation rice retinol carotenes women food intake Background: Vitamin A deficiency continues to be a major public health problem affecting developing countries where people eat mostly rice as a staple food. In Asia, rice provides up to 80% of the total daily energy intake. Objective: We used existing data sets from Bangladesh, Indonesia, and the Philippines, where dietary intakes have been quantified at the individual level to 1) determine the rice and vitamin A intake in nonpregnant, nonlactating women of reproductive age and in nonbreastfed children 1–3 y old and 2) simulate the amount of change that could be achieved in the prevalence of inadequate intake of vitamin A if rice biofortified with β-carotene were consumed instead of the rice consumed at present. Design: We considered a range of 4–20 parts per million (ppm) of β-carotene content and 10–70% substitution levels for the biofortified rice. Software was used to estimate usual rice and vitamin A intake for the simulation analyses. Results: In an analysis by country, the substitution of biofortified rice for white rice in the optimistic scenario (20 ppm and 70% substitution) decreased the prevalence of vitamin A inadequacy from baseline 78% in women and 71% in children in Bangladesh. In Indonesia and the Philippines, the prevalence of inadequacy fell by 55–60% in women and dropped by nearly 30% in children from baseline. Conclusions: The results of the simulation analysis were striking in that even low substitution levels and modest increases in the β-carotene of rice produced a meaningful decrease in the prevalence of inadequate intake of vitamin A. Increasing the substitution levels had a greater impact than increasing the β-carotene content by >12 ppm. 2016-08-18 2024-06-21T09:06:54Z 2024-06-21T09:06:54Z Journal Article https://hdl.handle.net/10568/146393 en Open Access Elsevier De Moura, Fabiana F.; Moursi, Mourad; Angel, Moira Donahue; Angeles-Agdeppa, Imelda; Atmarita, Atmarita; Gironella, Glen M.; Muslimatun; and Carriquiry, Alicia. 2016. Biofortified b-carotene rice improves vitamin A intake and reduces the prevalence of inadequacy among women and young children in a simulated analysis in Bangladesh, Indonesia, and the Philippines. American Journal of Clinical Nutrition 104(3): 769 - 775. https://doi.org/10.3945/ajcn.115.129270
spellingShingle carotenoids
gender
biofortification
simulation
rice
retinol
carotenes
women
food intake
De Moura, Fabiana F.
Moursi, Mourad
Angel, Moira Donahue
Angeles-Agdeppa, Imelda
Atmarita, Atmarita
Gironella, Glen M.
Muslimatun
Carriquiry, Alicia
Biofortified b-carotene rice improves vitamin A intake and reduces the prevalence of inadequacy among women and young children in a simulated analysis in Bangladesh, Indonesia, and the Philippines
title Biofortified b-carotene rice improves vitamin A intake and reduces the prevalence of inadequacy among women and young children in a simulated analysis in Bangladesh, Indonesia, and the Philippines
title_full Biofortified b-carotene rice improves vitamin A intake and reduces the prevalence of inadequacy among women and young children in a simulated analysis in Bangladesh, Indonesia, and the Philippines
title_fullStr Biofortified b-carotene rice improves vitamin A intake and reduces the prevalence of inadequacy among women and young children in a simulated analysis in Bangladesh, Indonesia, and the Philippines
title_full_unstemmed Biofortified b-carotene rice improves vitamin A intake and reduces the prevalence of inadequacy among women and young children in a simulated analysis in Bangladesh, Indonesia, and the Philippines
title_short Biofortified b-carotene rice improves vitamin A intake and reduces the prevalence of inadequacy among women and young children in a simulated analysis in Bangladesh, Indonesia, and the Philippines
title_sort biofortified b carotene rice improves vitamin a intake and reduces the prevalence of inadequacy among women and young children in a simulated analysis in bangladesh indonesia and the philippines
topic carotenoids
gender
biofortification
simulation
rice
retinol
carotenes
women
food intake
url https://hdl.handle.net/10568/146393
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