Increased iron status during a feeding trial of iron-biofortified beans increases physical work efficiency in Rwandan women
Background Iron-biofortified staple foods can improve iron status and resolve iron deficiency. However, whether improved iron status from iron biofortification can improve physical performance remains unclear. Objective This study aimed to examine whether changes in iron status from an iron-bioforti...
| Autores principales: | , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
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American Society for Nutrition
2020
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| Acceso en línea: | https://hdl.handle.net/10568/142753 |
| _version_ | 1855521195173085184 |
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| author | Luna, Sarah V. Pompano, Laura M. Lung'aho, Mercy Gahutu, Jean Bosco Haas, Jere D. |
| author_browse | Gahutu, Jean Bosco Haas, Jere D. Luna, Sarah V. Lung'aho, Mercy Pompano, Laura M. |
| author_facet | Luna, Sarah V. Pompano, Laura M. Lung'aho, Mercy Gahutu, Jean Bosco Haas, Jere D. |
| author_sort | Luna, Sarah V. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Background Iron-biofortified staple foods can improve iron status and resolve iron deficiency. However, whether improved iron status from iron biofortification can improve physical performance remains unclear. Objective This study aimed to examine whether changes in iron status from an iron-biofortified bean intervention affect work efficiency. Methods A total of 125 iron-depleted (ferritin <20 μg/L) female Rwandan university students (18–26 y) were selected from a larger sample randomly assigned to consume iron-biofortified beans (Fe-Bean; 86.1 mg Fe/kg) or conventional beans (control: 50.6 mg Fe/kg) twice daily for 18 wk (average of 314 g beans consumed/d). Blood biomarkers of iron status (primary outcome) and physical work efficiency (secondary outcome) were measured before and after the intervention. Work performed was assessed during 5-min steady-state periods at 0-, 25-, and 40-W workloads using a mechanically braked cycle ergometer. Work efficiency was calculated at 25 W and 40 W as the work accomplished divided by the energy expended at that workload above that expended at 0 W. General linear models were used to evaluate the relation between changes in iron status biomarkers and work efficiency. Results The Fe-Bean intervention had significant positive effects on hemoglobin, serum ferritin, and body iron stores but did not affect work efficiency. However, 18-wk change in hemoglobin was positively related to work efficiency at 40 W in the full sample (n = 119; estimate: 0.24 g/L; 95% CI: 0.01, 0.48 g/L; P = 0.044) and among women who were anemic (hemoglobin <120 g/L) at baseline (n = 43; estimate: 0.64 g/L; 95% CI: 0.05, 1.23 g/L; P = 0.036). Among women who were nonanemic at baseline, change in serum ferritin was positively related to change in work efficiency at 40 W (n = 60; estimate: 0.50 μg/L; 95% CI: 0.06, 0.95 μg/L; P = 0.027). Conclusions Increasing iron status during an iron-biofortified bean feeding trial improves work efficiency in iron-depleted, sedentary women. This trial was registered at clinicaltrials.gov as NCT01594359. |
| format | Journal Article |
| id | CGSpace142753 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2020 |
| publishDateRange | 2020 |
| publishDateSort | 2020 |
| publisher | American Society for Nutrition |
| publisherStr | American Society for Nutrition |
| record_format | dspace |
| spelling | CGSpace1427532024-10-25T07:55:14Z Increased iron status during a feeding trial of iron-biofortified beans increases physical work efficiency in Rwandan women Luna, Sarah V. Pompano, Laura M. Lung'aho, Mercy Gahutu, Jean Bosco Haas, Jere D. iron deficiency chlorosis efficiency anaemia gender biofortification physical activity work capacity trace elements beans iron women Background Iron-biofortified staple foods can improve iron status and resolve iron deficiency. However, whether improved iron status from iron biofortification can improve physical performance remains unclear. Objective This study aimed to examine whether changes in iron status from an iron-biofortified bean intervention affect work efficiency. Methods A total of 125 iron-depleted (ferritin <20 μg/L) female Rwandan university students (18–26 y) were selected from a larger sample randomly assigned to consume iron-biofortified beans (Fe-Bean; 86.1 mg Fe/kg) or conventional beans (control: 50.6 mg Fe/kg) twice daily for 18 wk (average of 314 g beans consumed/d). Blood biomarkers of iron status (primary outcome) and physical work efficiency (secondary outcome) were measured before and after the intervention. Work performed was assessed during 5-min steady-state periods at 0-, 25-, and 40-W workloads using a mechanically braked cycle ergometer. Work efficiency was calculated at 25 W and 40 W as the work accomplished divided by the energy expended at that workload above that expended at 0 W. General linear models were used to evaluate the relation between changes in iron status biomarkers and work efficiency. Results The Fe-Bean intervention had significant positive effects on hemoglobin, serum ferritin, and body iron stores but did not affect work efficiency. However, 18-wk change in hemoglobin was positively related to work efficiency at 40 W in the full sample (n = 119; estimate: 0.24 g/L; 95% CI: 0.01, 0.48 g/L; P = 0.044) and among women who were anemic (hemoglobin <120 g/L) at baseline (n = 43; estimate: 0.64 g/L; 95% CI: 0.05, 1.23 g/L; P = 0.036). Among women who were nonanemic at baseline, change in serum ferritin was positively related to change in work efficiency at 40 W (n = 60; estimate: 0.50 μg/L; 95% CI: 0.06, 0.95 μg/L; P = 0.027). Conclusions Increasing iron status during an iron-biofortified bean feeding trial improves work efficiency in iron-depleted, sedentary women. This trial was registered at clinicaltrials.gov as NCT01594359. 2020-03-01 2024-05-22T12:10:59Z 2024-05-22T12:10:59Z Journal Article https://hdl.handle.net/10568/142753 en https://dx.doi.org/10.3945%2Fjn.117.255356 https://doi.org/10.3945/jn.115.224741 Open Access American Society for Nutrition Luna, Sarah V.; Pompano, Laura M.; Lung'aho, Mercy; Gahutu, Jean Bosco; and Haas, Jere D. 2020. Increased iron status during a feeding trial of iron-biofortified beans increases physical work efficiency in Rwandan women. Journal of Nutrition 150(5): 1093–1099. https://doi.org/10.1093/jn/nxaa016 |
| spellingShingle | iron deficiency chlorosis efficiency anaemia gender biofortification physical activity work capacity trace elements beans iron women Luna, Sarah V. Pompano, Laura M. Lung'aho, Mercy Gahutu, Jean Bosco Haas, Jere D. Increased iron status during a feeding trial of iron-biofortified beans increases physical work efficiency in Rwandan women |
| title | Increased iron status during a feeding trial of iron-biofortified beans increases physical work efficiency in Rwandan women |
| title_full | Increased iron status during a feeding trial of iron-biofortified beans increases physical work efficiency in Rwandan women |
| title_fullStr | Increased iron status during a feeding trial of iron-biofortified beans increases physical work efficiency in Rwandan women |
| title_full_unstemmed | Increased iron status during a feeding trial of iron-biofortified beans increases physical work efficiency in Rwandan women |
| title_short | Increased iron status during a feeding trial of iron-biofortified beans increases physical work efficiency in Rwandan women |
| title_sort | increased iron status during a feeding trial of iron biofortified beans increases physical work efficiency in rwandan women |
| topic | iron deficiency chlorosis efficiency anaemia gender biofortification physical activity work capacity trace elements beans iron women |
| url | https://hdl.handle.net/10568/142753 |
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