Control of inbreeding in dairy cattle in the genomic era
This review evaluates the effects of inbreeding and inbreeding depression on the productivity of dairy cattle (Bos taurus), how genomic selection can control and decrease inbreeding and lethal inherited diseases related to the inbreeding. The relatedness and inbreeding have increased within populati...
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| Format: | First cycle, G2E |
| Language: | Swedish Inglés |
| Published: |
2015
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| Online Access: | https://stud.epsilon.slu.se/8381/ |
| Summary: | This review evaluates the effects of inbreeding and inbreeding depression on the productivity of dairy cattle (Bos taurus), how genomic selection can control and decrease inbreeding and lethal inherited diseases related to the inbreeding. The relatedness and inbreeding have increased within populations since only a few elite sires are used in today’s dairy cattle breeding practice. An increase of inbreeding results in an increased level of homozygosity, and thereby inbreeding depression and inherited diseases which influence production, reproduction and health traits negatively. Through molecular genetics and analysis of haplotypes that are common in the population but are never found as homozygotes, lethal recessive alleles can be identified. Publishing the test result of animals used in breeding allows for avoidance of at-risk matings with otherwise severe consequences. |
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