Control of inbreeding in dairy cattle in the genomic era
This review evaluates the effects of inbreeding and inbreeding depression on the productivity of dairy cattle (Bos taurus), how genomic selection can control and decrease inbreeding and lethal inherited diseases related to the inbreeding. The relatedness and inbreeding have increased within populati...
| Autor principal: | |
|---|---|
| Formato: | First cycle, G2E |
| Lenguaje: | sueco Inglés |
| Publicado: |
2015
|
| Materias: | |
| Acceso en línea: | https://stud.epsilon.slu.se/8381/ |
| _version_ | 1855571341884784640 |
|---|---|
| author | Gullstrand, Patricia |
| author_browse | Gullstrand, Patricia |
| author_facet | Gullstrand, Patricia |
| author_sort | Gullstrand, Patricia |
| collection | Epsilon Archive for Student Projects |
| description | This review evaluates the effects of inbreeding and inbreeding depression on the productivity of dairy cattle (Bos taurus), how genomic selection can control and decrease inbreeding and lethal inherited diseases related to the inbreeding. The relatedness and inbreeding have increased within populations since only a few elite sires are used in today’s dairy cattle breeding practice. An increase of inbreeding results in an increased level of homozygosity, and thereby inbreeding depression and inherited diseases which influence production, reproduction and health traits negatively. Through molecular genetics and analysis of haplotypes that are common in the population but are never found as homozygotes, lethal recessive alleles can be identified. Publishing the test result of animals used in breeding allows for avoidance of at-risk matings with otherwise severe consequences. |
| format | First cycle, G2E |
| id | RepoSLU8381 |
| institution | Swedish University of Agricultural Sciences |
| language | Swedish Inglés |
| publishDate | 2015 |
| publishDateSort | 2015 |
| record_format | eprints |
| spelling | RepoSLU83812015-08-24T09:29:18Z https://stud.epsilon.slu.se/8381/ Control of inbreeding in dairy cattle in the genomic era Gullstrand, Patricia Animal genetics and breeding This review evaluates the effects of inbreeding and inbreeding depression on the productivity of dairy cattle (Bos taurus), how genomic selection can control and decrease inbreeding and lethal inherited diseases related to the inbreeding. The relatedness and inbreeding have increased within populations since only a few elite sires are used in today’s dairy cattle breeding practice. An increase of inbreeding results in an increased level of homozygosity, and thereby inbreeding depression and inherited diseases which influence production, reproduction and health traits negatively. Through molecular genetics and analysis of haplotypes that are common in the population but are never found as homozygotes, lethal recessive alleles can be identified. Publishing the test result of animals used in breeding allows for avoidance of at-risk matings with otherwise severe consequences. Denna litteraturstudie utvärderar effekterna av inavel och inavelsdepression på produktivitet hos mjölkkor (Bos taurus), och hur genomisk selektion kan användas för att kontrollera samt minska inavel och förekomsten av ärftliga, dödliga sjukdomar relaterade till inaveln. Medelsläktskapet och inavelsgraden har ökat inom mjölkkopopulationer då endast ett fåtal elittjurar används i dagens mjölkkoavel. En ökad inavel resulterar i en ökad nivå av homozygositet, inavelsdepression och ärftliga sjukdomar, vilka påverkar produktion, reproduktion samt hälsoegenskaper negativt. Med molekylärgenetiska metoder och analyser av vanligt förekommande haplotyper som aldrig återfinns som homozygota kan man identifiera dödliga recessiva alleler. Genom att publicera provsvar från avelsdjur kan riskfyllda parningar, som annars ger allvarliga konsekvenser, undvikas. 2015-08-17 First cycle, G2E NonPeerReviewed application/pdf sv https://stud.epsilon.slu.se/8381/17/gullstrand_p_150824.pdf Gullstrand, Patricia, 2015. Control of inbreeding in dairy cattle in the genomic era. First cycle, G2E. Uppsala: (VH) > Dept. of Animal Breeding and Genetics (until 231231) <https://stud.epsilon.slu.se/view/divisions/OID-670.html> urn:nbn:se:slu:epsilon-s-4758 eng |
| spellingShingle | Animal genetics and breeding Gullstrand, Patricia Control of inbreeding in dairy cattle in the genomic era |
| title | Control of inbreeding in dairy cattle in the genomic era |
| title_full | Control of inbreeding in dairy cattle in the genomic era |
| title_fullStr | Control of inbreeding in dairy cattle in the genomic era |
| title_full_unstemmed | Control of inbreeding in dairy cattle in the genomic era |
| title_short | Control of inbreeding in dairy cattle in the genomic era |
| title_sort | control of inbreeding in dairy cattle in the genomic era |
| topic | Animal genetics and breeding |
| url | https://stud.epsilon.slu.se/8381/ https://stud.epsilon.slu.se/8381/ |