Laktatnivån i blodet : en prognostisk markör för tikar med pyometra?

The purpose of the present study was to explore if blood lactate levels are increased in bitches with pyometra, and if the lactate measurement could be used as a prognostic indicator and to determine outcome. The present study included 16 bitches with pyometra that were admitted to the University A...

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Autor principal: Bergström Ledin, Hanna
Formato: L3
Lenguaje:sueco
Inglés
Publicado: SLU/Dept. of Clinical Sciences (until 231231) 2011
Materias:
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author Bergström Ledin, Hanna
author_browse Bergström Ledin, Hanna
author_facet Bergström Ledin, Hanna
author_sort Bergström Ledin, Hanna
collection Epsilon Archive for Student Projects
description The purpose of the present study was to explore if blood lactate levels are increased in bitches with pyometra, and if the lactate measurement could be used as a prognostic indicator and to determine outcome. The present study included 16 bitches with pyometra that were admitted to the University Animal Hospital, Swedish University of Agricultural Sciences, Uppsala, Sweden. For comparison, a control group consisting of 14 healthy staffowned bitches was also evaluated. In all bitches, a physical examination was performed and blood samples for analysis of haematological and biochemical parameters were obtained. In all bitches with pyometra, surgical ovariohysterectomy was performed and a uterine sample for bacteriological culture and identification was collected. The diagnosis pyometra was subsequently confirmed by post-surgical pathological examination. In conclusion, there was no significant difference in the preoperative blood lactate levels between bitches with pyometra and healthy control bitches. Increased blood lactate levels were not associated with longer hospitalization. According to the results of the present pilot study, a single preoperative lactate measurement is not a valuable prognostic marker for pyometra bitches in general. If the present study had included a larger number of bitches or the selected individuals been more severely affected by their disease, at least a few patients with distinctly increased blood lactate levels could have been expected. Still, lactate analysis is probably valuable for prognosis, optimizing treatment and monitoring of the individual patient where extraordinary levels are demonstrated. The value of repeated lactate measurement for those patients still remains to be evaluated.
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institution Swedish University of Agricultural Sciences
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Inglés
publishDate 2011
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spelling RepoSLU53452013-03-25T13:12:50Z Laktatnivån i blodet : en prognostisk markör för tikar med pyometra? Bergström Ledin, Hanna Laktat Prognostisk markör Pyometra Hund Tik The purpose of the present study was to explore if blood lactate levels are increased in bitches with pyometra, and if the lactate measurement could be used as a prognostic indicator and to determine outcome. The present study included 16 bitches with pyometra that were admitted to the University Animal Hospital, Swedish University of Agricultural Sciences, Uppsala, Sweden. For comparison, a control group consisting of 14 healthy staffowned bitches was also evaluated. In all bitches, a physical examination was performed and blood samples for analysis of haematological and biochemical parameters were obtained. In all bitches with pyometra, surgical ovariohysterectomy was performed and a uterine sample for bacteriological culture and identification was collected. The diagnosis pyometra was subsequently confirmed by post-surgical pathological examination. In conclusion, there was no significant difference in the preoperative blood lactate levels between bitches with pyometra and healthy control bitches. Increased blood lactate levels were not associated with longer hospitalization. According to the results of the present pilot study, a single preoperative lactate measurement is not a valuable prognostic marker for pyometra bitches in general. If the present study had included a larger number of bitches or the selected individuals been more severely affected by their disease, at least a few patients with distinctly increased blood lactate levels could have been expected. Still, lactate analysis is probably valuable for prognosis, optimizing treatment and monitoring of the individual patient where extraordinary levels are demonstrated. The value of repeated lactate measurement for those patients still remains to be evaluated. SLU/Dept. of Clinical Sciences (until 231231) 2011 L3 swe eng https://stud.epsilon.slu.se/5345/
spellingShingle Laktat
Prognostisk markör
Pyometra
Hund
Tik
Bergström Ledin, Hanna
Laktatnivån i blodet : en prognostisk markör för tikar med pyometra?
title Laktatnivån i blodet : en prognostisk markör för tikar med pyometra?
title_full Laktatnivån i blodet : en prognostisk markör för tikar med pyometra?
title_fullStr Laktatnivån i blodet : en prognostisk markör för tikar med pyometra?
title_full_unstemmed Laktatnivån i blodet : en prognostisk markör för tikar med pyometra?
title_short Laktatnivån i blodet : en prognostisk markör för tikar med pyometra?
title_sort laktatnivån i blodet : en prognostisk markör för tikar med pyometra?
topic Laktat
Prognostisk markör
Pyometra
Hund
Tik