Aortic Body Tumors in Dogs

The purpose of this essay was to review the literature and describe the patophysiology, diagnosis, microscopic and macroscopic appearance of aortic body tumors in dogs. The tumors originate from the chemoreceptor organs situated at the base of the heart. The chemoreceptor organs are neuroendocrine c...

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Autor principal: Eriksson, Malin
Formato: First cycle, G2E
Lenguaje:sueco
Inglés
Publicado: 2011
Materias:
Acceso en línea:https://stud.epsilon.slu.se/2545/
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author Eriksson, Malin
author_browse Eriksson, Malin
author_facet Eriksson, Malin
author_sort Eriksson, Malin
collection Epsilon Archive for Student Projects
description The purpose of this essay was to review the literature and describe the patophysiology, diagnosis, microscopic and macroscopic appearance of aortic body tumors in dogs. The tumors originate from the chemoreceptor organs situated at the base of the heart. The chemoreceptor organs are neuroendocrine cells responsible for surveillance of changes in e.g. the blood pH. Aortic body tumors are rare and represent 7 % of the total cases of primary cardiac tumors in canines. Despite their low prevalence the tumors are the second most common cardiac tumor. However, they are of clinical importance because they can cause cardiac failure and cardiac tamponade among other symptoms. Brachycephalic breeds such as Boxers, Boston bull terriers and English bulldogs have a high prevalence. However, there are other brachycephalic breeds e.g. Pugs where the prevalence is not higher than the average among all breeds. The etiology is not fully known but reports indicate a genetic and/or breed predisposition. Theories suggest that chronic hypoxia and “Brachycephalic airway syndrome” serves as contributing factors. The tumors measure 0,5 – 12,5 cm in diameter and the size of the tumor determines the symptoms including cardiac failure and cardiac tamponade. A benignant behavior is mostly seen and the tumors are expansive which causes many of the symptoms. There are also infiltrative tumors and they cause symptoms as well though they are less common. Tumors can be discovered by ultrasonography or radiography and diagnosis can be confirmed with histological stains such as hematoxylin and eosin staining together with immunohistochemistry by labeling the tumor with a neuroendocrine marker e.g. chromogranin A. 
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spelling RepoSLU25452012-04-20T14:19:08Z https://stud.epsilon.slu.se/2545/ Aortic Body Tumors in Dogs Eriksson, Malin Animal diseases The purpose of this essay was to review the literature and describe the patophysiology, diagnosis, microscopic and macroscopic appearance of aortic body tumors in dogs. The tumors originate from the chemoreceptor organs situated at the base of the heart. The chemoreceptor organs are neuroendocrine cells responsible for surveillance of changes in e.g. the blood pH. Aortic body tumors are rare and represent 7 % of the total cases of primary cardiac tumors in canines. Despite their low prevalence the tumors are the second most common cardiac tumor. However, they are of clinical importance because they can cause cardiac failure and cardiac tamponade among other symptoms. Brachycephalic breeds such as Boxers, Boston bull terriers and English bulldogs have a high prevalence. However, there are other brachycephalic breeds e.g. Pugs where the prevalence is not higher than the average among all breeds. The etiology is not fully known but reports indicate a genetic and/or breed predisposition. Theories suggest that chronic hypoxia and “Brachycephalic airway syndrome” serves as contributing factors. The tumors measure 0,5 – 12,5 cm in diameter and the size of the tumor determines the symptoms including cardiac failure and cardiac tamponade. A benignant behavior is mostly seen and the tumors are expansive which causes many of the symptoms. There are also infiltrative tumors and they cause symptoms as well though they are less common. Tumors can be discovered by ultrasonography or radiography and diagnosis can be confirmed with histological stains such as hematoxylin and eosin staining together with immunohistochemistry by labeling the tumor with a neuroendocrine marker e.g. chromogranin A.  2011-05-02 First cycle, G2E NonPeerReviewed application/pdf swe https://stud.epsilon.slu.se/2545/1/Eriksson_m_110502.pdf Eriksson, Malin, 2011. Aortic Body Tumors in Dogs. First cycle, G2E. Uppsala: (VH) > Dept. of Biomedical Sciences and Veterinary Public Health (until 231231) <https://stud.epsilon.slu.se/view/divisions/OID-713.html> urn:nbn:se:slu:epsilon-s-105 eng
spellingShingle Animal diseases
Eriksson, Malin
Aortic Body Tumors in Dogs
title Aortic Body Tumors in Dogs
title_full Aortic Body Tumors in Dogs
title_fullStr Aortic Body Tumors in Dogs
title_full_unstemmed Aortic Body Tumors in Dogs
title_short Aortic Body Tumors in Dogs
title_sort aortic body tumors in dogs
topic Animal diseases
url https://stud.epsilon.slu.se/2545/
https://stud.epsilon.slu.se/2545/