Why choose the rabbit to work in reproductive technology?
Rabbits have played a significant role in both livestock production and the advancement of reproductive scientific research. Their unique biological traits, including induced ovulation and a reproductive process that closely mirrors that of humans, have been pivotal in their use as a model. Moreo...
| Main Authors: | , , |
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| Format: | article |
| Language: | Inglés |
| Published: |
Wiley
2025
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| Subjects: | |
| Online Access: | https://hdl.handle.net/20.500.11939/9032 https://onlinelibrary.wiley.com/doi/10.1111/rda.14640 |
| Summary: | Rabbits have played a significant role in both livestock production and the advancement
of reproductive scientific research. Their unique biological traits, including induced
ovulation and a reproductive process that closely mirrors that of humans, have
been pivotal in their use as a model. Moreover, their body size is perfectly aligned
with the 3Rs principles: Replacement, Reduction, and Refinement. Consequently,
techniques for gamete collection and embryo recovery, followed by their use in artificial
insemination or embryo transfer, are characterized by being minimally invasive.
However, refining in vitro fertilization and embryo culture techniques continues to
present challenges. The incorporation of cutting-edge
genomic editing tools, such as
CRISPR/Cas9, has reestablished rabbits as essential models in genetic and biomedical
research, driving scientific progress. This review aims to describe the most effective
reproductive biotechnologies for both male and female rabbits and how these
methodologies are in line with the 3Rs principles—Replacement, Reduction, and
Refinement—highlighting their significance in conducting ethical research. |
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