Why choose the rabbit to work in reproductive technology?
Rabbits have played a significant role in both livestock production and the advancement of reproductive scientific research. Their unique biological traits, including induced ovulation and a reproductive process that closely mirrors that of humans, have been pivotal in their use as a model. Moreo...
| Autores principales: | , , |
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| Formato: | Artículo |
| Lenguaje: | Inglés |
| Publicado: |
Wiley
2025
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| Acceso en línea: | https://hdl.handle.net/20.500.11939/9032 https://onlinelibrary.wiley.com/doi/10.1111/rda.14640 |
| _version_ | 1855492610747006976 |
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| author | Marco-Jiménez, Francisco Viudes-De-Castro, María P. Vicente, José S. |
| author_browse | Marco-Jiménez, Francisco Vicente, José S. Viudes-De-Castro, María P. |
| author_facet | Marco-Jiménez, Francisco Viudes-De-Castro, María P. Vicente, José S. |
| author_sort | Marco-Jiménez, Francisco |
| collection | ReDivia |
| description | Rabbits have played a significant role in both livestock production and the advancement
of reproductive scientific research. Their unique biological traits, including induced
ovulation and a reproductive process that closely mirrors that of humans, have
been pivotal in their use as a model. Moreover, their body size is perfectly aligned
with the 3Rs principles: Replacement, Reduction, and Refinement. Consequently,
techniques for gamete collection and embryo recovery, followed by their use in artificial
insemination or embryo transfer, are characterized by being minimally invasive.
However, refining in vitro fertilization and embryo culture techniques continues to
present challenges. The incorporation of cutting-edge
genomic editing tools, such as
CRISPR/Cas9, has reestablished rabbits as essential models in genetic and biomedical
research, driving scientific progress. This review aims to describe the most effective
reproductive biotechnologies for both male and female rabbits and how these
methodologies are in line with the 3Rs principles—Replacement, Reduction, and
Refinement—highlighting their significance in conducting ethical research. |
| format | Artículo |
| id | ReDivia9032 |
| institution | Instituto Valenciano de Investigaciones Agrarias (IVIA) |
| language | Inglés |
| publishDate | 2025 |
| publishDateRange | 2025 |
| publishDateSort | 2025 |
| publisher | Wiley |
| publisherStr | Wiley |
| record_format | dspace |
| spelling | ReDivia90322025-04-25T14:49:50Z Why choose the rabbit to work in reproductive technology? Marco-Jiménez, Francisco Viudes-De-Castro, María P. Vicente, José S. animal model editing embryo L53 Animal physiology - Reproduction Ai (artificial insemination) Cryopreservation Livestock Oocytes Superovulation Rabbits have played a significant role in both livestock production and the advancement of reproductive scientific research. Their unique biological traits, including induced ovulation and a reproductive process that closely mirrors that of humans, have been pivotal in their use as a model. Moreover, their body size is perfectly aligned with the 3Rs principles: Replacement, Reduction, and Refinement. Consequently, techniques for gamete collection and embryo recovery, followed by their use in artificial insemination or embryo transfer, are characterized by being minimally invasive. However, refining in vitro fertilization and embryo culture techniques continues to present challenges. The incorporation of cutting-edge genomic editing tools, such as CRISPR/Cas9, has reestablished rabbits as essential models in genetic and biomedical research, driving scientific progress. This review aims to describe the most effective reproductive biotechnologies for both male and female rabbits and how these methodologies are in line with the 3Rs principles—Replacement, Reduction, and Refinement—highlighting their significance in conducting ethical research. 2025-02-24T11:26:26Z 2025-02-24T11:26:26Z 2024 article publishedVersion Marco‐Jiménez, F., Viudes‐de‐Castro, M. P., & Vicente, J. S. (2024). Why choose the rabbit to work in reproductive technology?. Reproduction in Domestic Animals, 59, e14640. 0936-6768 1439-0531 https://hdl.handle.net/20.500.11939/9032 10.1111/rda.14640 https://onlinelibrary.wiley.com/doi/10.1111/rda.14640 en info:eu-repo/grantAgreement/AEI/Programa Estatal de Generación de Conocimiento y Fortalecimiento Científico y Tecnológico del Sistema de I+D+i/PID2021-127867OB-100 info:eu-repo/grantAgreement/AEI/Programa Estatal de I+D+i orientada a los Retos de la Sociedad/PDC2021-120767-100/ES/DISPOSITIVO PARA LA VITRIFICACION DE OVULOS Y EMBRIONES EN ESPECIES GANADERAS Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ openAccess Wiley electronico |
| spellingShingle | animal model editing embryo L53 Animal physiology - Reproduction Ai (artificial insemination) Cryopreservation Livestock Oocytes Superovulation Marco-Jiménez, Francisco Viudes-De-Castro, María P. Vicente, José S. Why choose the rabbit to work in reproductive technology? |
| title | Why choose the rabbit to work in reproductive technology? |
| title_full | Why choose the rabbit to work in reproductive technology? |
| title_fullStr | Why choose the rabbit to work in reproductive technology? |
| title_full_unstemmed | Why choose the rabbit to work in reproductive technology? |
| title_short | Why choose the rabbit to work in reproductive technology? |
| title_sort | why choose the rabbit to work in reproductive technology |
| topic | animal model editing embryo L53 Animal physiology - Reproduction Ai (artificial insemination) Cryopreservation Livestock Oocytes Superovulation |
| url | https://hdl.handle.net/20.500.11939/9032 https://onlinelibrary.wiley.com/doi/10.1111/rda.14640 |
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