Genetic characterization of bovine herpesvirus 4 (BoHV-4) isolates from Argentine cattle suggests a complex evolutionary scenario
Bovine herpevsirus 4 (BoHV-4) is a gammaherpesvirus that has been associated with different clinical conditions in cattle. In Argentina, BoHV-4 was detected in diverse bovine samples. The aim of this study was to analyze the genetic relationship of 48 field BoHV-4 strains isolated from cattle in Arg...
| Autores principales: | , , , , , , , , , , , |
|---|---|
| Formato: | info:ar-repo/semantics/artículo |
| Lenguaje: | Inglés |
| Publicado: |
Springer Nature
2020
|
| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12123/7744 https://link.springer.com/article/10.1007/s11033-020-05449-9 https://doi.org/10.1007/s11033-020-05449-9 |
| _version_ | 1855035913347792896 |
|---|---|
| author | Perez, Sandra Manrique, Julieta Moran, Pedro Romeo, Florencia Angelini, Hernán Pablo Leunda, Maria Rosa Pereyra, Susana Beatriz Spetter, Lucas Maximiliano Gonzalez Altamiranda, Erika Odeon, Anselmo Carlos Jones, Leandro Verna, Andrea Elizabeth |
| author_browse | Angelini, Hernán Pablo Gonzalez Altamiranda, Erika Jones, Leandro Leunda, Maria Rosa Manrique, Julieta Moran, Pedro Odeon, Anselmo Carlos Pereyra, Susana Beatriz Perez, Sandra Romeo, Florencia Spetter, Lucas Maximiliano Verna, Andrea Elizabeth |
| author_facet | Perez, Sandra Manrique, Julieta Moran, Pedro Romeo, Florencia Angelini, Hernán Pablo Leunda, Maria Rosa Pereyra, Susana Beatriz Spetter, Lucas Maximiliano Gonzalez Altamiranda, Erika Odeon, Anselmo Carlos Jones, Leandro Verna, Andrea Elizabeth |
| author_sort | Perez, Sandra |
| collection | INTA Digital |
| description | Bovine herpevsirus 4 (BoHV-4) is a gammaherpesvirus that has been associated with different clinical conditions in cattle. In Argentina, BoHV-4 was detected in diverse bovine samples. The aim of this study was to analyze the genetic relationship of 48 field BoHV-4 strains isolated from cattle in Argentina. According to thymidine kinase (tk) gene sequences, BoHV-4 isolates belong to genotypes 1, 2 and 3. Phylogenetic analyses confirmed the presence of the three previously described viral genotypes. However, some of the studied isolates presented conflicting phylogenetic signals between the studied markers. This suggests a complex evolutionary background, that is a history of recombination, incomplete lineage sorting (deep coalescence) or a combination of these, which requires further study. These potential events make difficult the diagnosis of BoHV-4 from clinical samples of cattle and may pose a significant problem for the control of the virus in the herds. |
| format | info:ar-repo/semantics/artículo |
| id | INTA7744 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2020 |
| publishDateRange | 2020 |
| publishDateSort | 2020 |
| publisher | Springer Nature |
| publisherStr | Springer Nature |
| record_format | dspace |
| spelling | INTA77442020-08-20T12:28:56Z Genetic characterization of bovine herpesvirus 4 (BoHV-4) isolates from Argentine cattle suggests a complex evolutionary scenario Perez, Sandra Manrique, Julieta Moran, Pedro Romeo, Florencia Angelini, Hernán Pablo Leunda, Maria Rosa Pereyra, Susana Beatriz Spetter, Lucas Maximiliano Gonzalez Altamiranda, Erika Odeon, Anselmo Carlos Jones, Leandro Verna, Andrea Elizabeth Ganado Bovino Herpes Virus Bovino Filogenia Argentina Cattle Bovine Herpesvirus Phylogeny Bovine herpevsirus 4 (BoHV-4) is a gammaherpesvirus that has been associated with different clinical conditions in cattle. In Argentina, BoHV-4 was detected in diverse bovine samples. The aim of this study was to analyze the genetic relationship of 48 field BoHV-4 strains isolated from cattle in Argentina. According to thymidine kinase (tk) gene sequences, BoHV-4 isolates belong to genotypes 1, 2 and 3. Phylogenetic analyses confirmed the presence of the three previously described viral genotypes. However, some of the studied isolates presented conflicting phylogenetic signals between the studied markers. This suggests a complex evolutionary background, that is a history of recombination, incomplete lineage sorting (deep coalescence) or a combination of these, which requires further study. These potential events make difficult the diagnosis of BoHV-4 from clinical samples of cattle and may pose a significant problem for the control of the virus in the herds. EEA Balcarce Fil: Pérez, Sandra. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina. Fil: Manrique, Julieta. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina; Argentina. Universidad Nacional de la Patagonia San Juan Bosco. Facultad de Ciencias Naturales y Ciencias de La Salud; Argentina. Fil: Morán, Pedro. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; Argentina. Fil: Romeo, Florencia. Agencia Nacional de Promoción Científica y Tecnológica; Argentina. Universidad Nacional de la Patagonia San Juan Bosco. Facultad de Ciencias Naturales Sede Trelew; Argentina Fil: Angelini, Hernán Pablo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Fil: Leunda, María Rosa. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Fil: Pereyra, Susana Beatriz. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Fil: Spetter, Maximiliano. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Fil: González Altamiranda, Erika. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Fil: Odeón, Anselmo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Fil: Jones, Leandro. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de la Patagonia San Juan Bosco. Facultad de Ciencias Naturales y Ciencias de La Salud; Argentina. Fil: Verna, Andrea. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. 2020-08-20T12:20:41Z 2020-08-20T12:20:41Z 2020-04 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/7744 https://link.springer.com/article/10.1007/s11033-020-05449-9 1573-4978 0301-4851 https://doi.org/10.1007/s11033-020-05449-9 eng info:eu-repo/semantics/restrictedAccess application/pdf Springer Nature Molecular Biology Reports 47 : 4905–4909 (2020) |
| spellingShingle | Ganado Bovino Herpes Virus Bovino Filogenia Argentina Cattle Bovine Herpesvirus Phylogeny Perez, Sandra Manrique, Julieta Moran, Pedro Romeo, Florencia Angelini, Hernán Pablo Leunda, Maria Rosa Pereyra, Susana Beatriz Spetter, Lucas Maximiliano Gonzalez Altamiranda, Erika Odeon, Anselmo Carlos Jones, Leandro Verna, Andrea Elizabeth Genetic characterization of bovine herpesvirus 4 (BoHV-4) isolates from Argentine cattle suggests a complex evolutionary scenario |
| title | Genetic characterization of bovine herpesvirus 4 (BoHV-4) isolates from Argentine cattle suggests a complex evolutionary scenario |
| title_full | Genetic characterization of bovine herpesvirus 4 (BoHV-4) isolates from Argentine cattle suggests a complex evolutionary scenario |
| title_fullStr | Genetic characterization of bovine herpesvirus 4 (BoHV-4) isolates from Argentine cattle suggests a complex evolutionary scenario |
| title_full_unstemmed | Genetic characterization of bovine herpesvirus 4 (BoHV-4) isolates from Argentine cattle suggests a complex evolutionary scenario |
| title_short | Genetic characterization of bovine herpesvirus 4 (BoHV-4) isolates from Argentine cattle suggests a complex evolutionary scenario |
| title_sort | genetic characterization of bovine herpesvirus 4 bohv 4 isolates from argentine cattle suggests a complex evolutionary scenario |
| topic | Ganado Bovino Herpes Virus Bovino Filogenia Argentina Cattle Bovine Herpesvirus Phylogeny |
| url | http://hdl.handle.net/20.500.12123/7744 https://link.springer.com/article/10.1007/s11033-020-05449-9 https://doi.org/10.1007/s11033-020-05449-9 |
| work_keys_str_mv | AT perezsandra geneticcharacterizationofbovineherpesvirus4bohv4isolatesfromargentinecattlesuggestsacomplexevolutionaryscenario AT manriquejulieta geneticcharacterizationofbovineherpesvirus4bohv4isolatesfromargentinecattlesuggestsacomplexevolutionaryscenario AT moranpedro geneticcharacterizationofbovineherpesvirus4bohv4isolatesfromargentinecattlesuggestsacomplexevolutionaryscenario AT romeoflorencia geneticcharacterizationofbovineherpesvirus4bohv4isolatesfromargentinecattlesuggestsacomplexevolutionaryscenario AT angelinihernanpablo geneticcharacterizationofbovineherpesvirus4bohv4isolatesfromargentinecattlesuggestsacomplexevolutionaryscenario AT leundamariarosa geneticcharacterizationofbovineherpesvirus4bohv4isolatesfromargentinecattlesuggestsacomplexevolutionaryscenario AT pereyrasusanabeatriz geneticcharacterizationofbovineherpesvirus4bohv4isolatesfromargentinecattlesuggestsacomplexevolutionaryscenario AT spetterlucasmaximiliano geneticcharacterizationofbovineherpesvirus4bohv4isolatesfromargentinecattlesuggestsacomplexevolutionaryscenario AT gonzalezaltamirandaerika geneticcharacterizationofbovineherpesvirus4bohv4isolatesfromargentinecattlesuggestsacomplexevolutionaryscenario AT odeonanselmocarlos geneticcharacterizationofbovineherpesvirus4bohv4isolatesfromargentinecattlesuggestsacomplexevolutionaryscenario AT jonesleandro geneticcharacterizationofbovineherpesvirus4bohv4isolatesfromargentinecattlesuggestsacomplexevolutionaryscenario AT vernaandreaelizabeth geneticcharacterizationofbovineherpesvirus4bohv4isolatesfromargentinecattlesuggestsacomplexevolutionaryscenario |