A dose-dependent response to MEK inhibition determines hypoblast fate in bovine embryos

Background: The segregation of the hypoblast and the emergence of the pluripotent epiblast mark the final stages of blastocyst formation in mammalian embryos. In bovine embryos the formation of the hypoblast has been partially studied, and evidence shows that MEK signalling plays a limited role in t...

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Bibliographic Details
Main Authors: Canizo, Jésica Romina, Ynsaurralde Rivolta, Amanda Eugenia, Vazquez Echegaray, Camila, Suvá, Mariana, Alberio, Virgilia, Aller Atucha, Juan Florencio, Guberman, Alejandra, Salamone, Daniel Felipe, Alberio, Ricardo, Alberio, Ramiro
Format: info:ar-repo/semantics/artículo
Language:Inglés
Published: BioMed Central 2019
Subjects:
Online Access:http://hdl.handle.net/20.500.12123/6009
https://bmcdevbiol.biomedcentral.com/articles/10.1186/s12861-019-0193-9
https://doi.org/10.1186/s12861-019-0193-9

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