A dose-dependent response to MEK inhibition determines hypoblast fate in bovine embryos

Background: The segregation of the hypoblast and the emergence of the pluripotent epiblast mark the final stages of blastocyst formation in mammalian embryos. In bovine embryos the formation of the hypoblast has been partially studied, and evidence shows that MEK signalling plays a limited role in t...

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Detalles Bibliográficos
Autores principales: Canizo, Jésica Romina, Ynsaurralde Rivolta, Amanda Eugenia, Vazquez Echegaray, Camila, Suvá, Mariana, Alberio, Virgilia, Aller Atucha, Juan Florencio, Guberman, Alejandra, Salamone, Daniel Felipe, Alberio, Ricardo, Alberio, Ramiro
Formato: info:ar-repo/semantics/artículo
Lenguaje:Inglés
Publicado: BioMed Central 2019
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12123/6009
https://bmcdevbiol.biomedcentral.com/articles/10.1186/s12861-019-0193-9
https://doi.org/10.1186/s12861-019-0193-9

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