Assessing Tn5 and sleeping beauty for transpositional transgenesis by cytoplasmic injection into bovine and ovine zygotes

Transgenic domestic animals represent an alternative to bioreactors for large-scale production of biopharmaceuticals and could also provide more accurate biomedical models than rodents. However, their generation remains inefficient. Recently, DNA transposons allowed improved transgenesis efficiencie...

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Autores principales:	Bevacqua, Romina Jimena, Fernández y Martin, Rafael, Canel, Natalia Gabriela, Gibbons, Alejandro Eduardo, Texeira, D.I.A., Lange, F., Vans Landschoot, Geraldina, Savy, Virginia, Briski, Olinda, Hiriart, María Inés, Grueso, Esther, Ivics, Zoltán, Taboga, Oscar Alberto, Kues, Wilfried A., Ferraris, S.R., Salamone, Daniel Felipe
Formato:	Artículo
Lenguaje:	Inglés
Publicado:	2017
Materias:	Ovinos Bovinae Cigotos Transferencia de Genes Inyección Brucelosis Sheep Zygotes Gene Transfer Injection Tn5
Acceso en línea:	http://hdl.handle.net/20.500.12123/559 http://journals.plos.org/plosone/article/related?id=10.1371/journal.pone.0174025 https://doi.org/10.1371/journal.pone.0174025