Developments in plant-based vaccines against diseases of concern in developing countries

Vaccination has been extensively used to prevent, eradicate and control infectious diseases. However, the development and implementation of new vaccines remains prohibitively expensive for middle and low income countries where such measures are surely needed most. The production of plant-based vac...

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Detalles Bibliográficos
Autores principales: Gomez, Evangelina Raquel, Chimeno Zoth, Silvina Andrea, Carrillo, Elisa Cristina, Berinstein, Analia
Formato: info:ar-repo/semantics/artículo
Lenguaje:Inglés
Publicado: BENTHAM Open 2019
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12123/4844
https://pdfs.semanticscholar.org/3b94/fb00aec731995ad4f6c2c08dbb69fbc1827a.pdf
Descripción
Sumario:Vaccination has been extensively used to prevent, eradicate and control infectious diseases. However, the development and implementation of new vaccines remains prohibitively expensive for middle and low income countries where such measures are surely needed most. The production of plant-based vaccines provides a promising alternative to create affordable biological products. In the past decade, a growing number of research groups worldwide have studied plant expression and parenteral or oral delivery of vaccine antigens, some showing promising potential. Here, we describe the basis of the system and the state of the art of developments regarding diseases of concern in developing countries.