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Efficacy of SAD (Berne) rabies vaccine given by the oral route in two species of jackal (Canis mesomelas and Canis adustus)

Eight black-backed jackals and seven side-striped jackals were given SAD (Berne) rabies vaccine by direct oral instillation. Three different vaccine doses were used: 106.3, 106.8 and 107.5 median tissue culture infectious doses. Two additional jackals were given vaccine in chicken heads. One group o...

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Autores principales: Bingham, J., Kappeler, A., Hill, F.W.G., King, A.A., Perry, Brian D.
Formato: Journal Article
Lenguaje:Inglés
Publicado: Wildlife Disease Association 1995
Materias:
wild animals
jackals
rabies
vaccination
experimental infection
disease control
oral administration
viroses
Acceso en línea:https://hdl.handle.net/10568/33024
Sumario:Eight black-backed jackals and seven side-striped jackals were given SAD (Berne) rabies vaccine by direct oral instillation. Three different vaccine doses were used: 106.3, 106.8 and 107.5 median tissue culture infectious doses. Two additional jackals were given vaccine in chicken heads. One group of jackals was challenged with a lethal dose of jackal-derived rabies virus 1 month and a second group 12 months after vaccination. All 17 vaccinated jackals developed high and persistent serum neutralizing antibody titres. All challenged jackals resisted a lethal dose of rabies virus, whereas 3 control jackals given the same challenge developed rabies.

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