Bovine colostral cells—the often forgotten component of colostrum

At birth, neonatal calves have all the essential immune components they need as adult cattle; however, it takes at least 2 to 4 weeks for those components to become fully functional.1,2 The immune system does not become completely mature until the animal is 5 to 8 months old; for example, it takes 8...

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Autores principales: Gonzalez, Diego, Dus Santos, Maria Jose
Formato: info:ar-repo/semantics/artículo
Lenguaje:Inglés
Publicado: American Veterinary Medical Association 2018
Materias:
Acceso en línea:https://avmajournals.avma.org/doi/abs/10.2460/javma.250.9.998?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&journalCode=javma
http://hdl.handle.net/20.500.12123/3995
https://doi.org/10.2460/javma.250.9.998
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author Gonzalez, Diego
Dus Santos, Maria Jose
author_browse Dus Santos, Maria Jose
Gonzalez, Diego
author_facet Gonzalez, Diego
Dus Santos, Maria Jose
author_sort Gonzalez, Diego
collection INTA Digital
description At birth, neonatal calves have all the essential immune components they need as adult cattle; however, it takes at least 2 to 4 weeks for those components to become fully functional.1,2 The immune system does not become completely mature until the animal is 5 to 8 months old; for example, it takes 8 months for T cells (CD4+, CD8+, and T-cell receptor gδ+ cells) to reach peak numbers.3 Thus, the immature immune system of young calves likely moderates rather than prevents disease. This does not imply that young (< 8 months old) calves cannot respond to antigens; it simply means that the response to those antigens is weaker, slower, and easier to overcome than it will be when the immune system is mature.4
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institution Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina)
language Inglés
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publishDateRange 2018
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publisher American Veterinary Medical Association
publisherStr American Veterinary Medical Association
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spelling INTA39952018-12-03T11:29:57Z Bovine colostral cells—the often forgotten component of colostrum Gonzalez, Diego Dus Santos, Maria Jose Colostrum Immune Response Antigens Vaccines Calves Calostro Respuesta Inmunológica Antígenos Vacuna Ternero At birth, neonatal calves have all the essential immune components they need as adult cattle; however, it takes at least 2 to 4 weeks for those components to become fully functional.1,2 The immune system does not become completely mature until the animal is 5 to 8 months old; for example, it takes 8 months for T cells (CD4+, CD8+, and T-cell receptor gδ+ cells) to reach peak numbers.3 Thus, the immature immune system of young calves likely moderates rather than prevents disease. This does not imply that young (< 8 months old) calves cannot respond to antigens; it simply means that the response to those antigens is weaker, slower, and easier to overcome than it will be when the immune system is mature.4 Instituto de Virología Fil: Gonzalez, Diego. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina Fil: Dus Santos, Maria Jose. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina 2018-12-03T11:25:58Z 2018-12-03T11:25:58Z 2017-05 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion https://avmajournals.avma.org/doi/abs/10.2460/javma.250.9.998?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&journalCode=javma http://hdl.handle.net/20.500.12123/3995 0003-1488 https://doi.org/10.2460/javma.250.9.998 eng info:eu-repo/semantics/restrictedAccess application/pdf American Veterinary Medical Association Journal of the American Veterinary Medical Association 250 (9) : 998-1005 (Mayo 2017)
spellingShingle Colostrum
Immune Response
Antigens
Vaccines
Calves
Calostro
Respuesta Inmunológica
Antígenos
Vacuna
Ternero
Gonzalez, Diego
Dus Santos, Maria Jose
Bovine colostral cells—the often forgotten component of colostrum
title Bovine colostral cells—the often forgotten component of colostrum
title_full Bovine colostral cells—the often forgotten component of colostrum
title_fullStr Bovine colostral cells—the often forgotten component of colostrum
title_full_unstemmed Bovine colostral cells—the often forgotten component of colostrum
title_short Bovine colostral cells—the often forgotten component of colostrum
title_sort bovine colostral cells the often forgotten component of colostrum
topic Colostrum
Immune Response
Antigens
Vaccines
Calves
Calostro
Respuesta Inmunológica
Antígenos
Vacuna
Ternero
url https://avmajournals.avma.org/doi/abs/10.2460/javma.250.9.998?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&journalCode=javma
http://hdl.handle.net/20.500.12123/3995
https://doi.org/10.2460/javma.250.9.998
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