Bovine colostral cells—the often forgotten component of colostrum
At birth, neonatal calves have all the essential immune components they need as adult cattle; however, it takes at least 2 to 4 weeks for those components to become fully functional.1,2 The immune system does not become completely mature until the animal is 5 to 8 months old; for example, it takes 8...
| Main Authors: | , |
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| Format: | info:ar-repo/semantics/artículo |
| Language: | Inglés |
| Published: |
American Veterinary Medical Association
2018
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| Subjects: | |
| Online Access: | https://avmajournals.avma.org/doi/abs/10.2460/javma.250.9.998?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&journalCode=javma http://hdl.handle.net/20.500.12123/3995 https://doi.org/10.2460/javma.250.9.998 |
| Summary: | At birth, neonatal calves have all the essential immune components they need as adult cattle; however, it takes at least 2 to 4 weeks for those components to become fully functional.1,2 The immune system does not become completely mature until the animal is 5 to 8 months old; for example, it takes 8 months for T cells (CD4+, CD8+, and T-cell receptor gδ+ cells) to reach peak numbers.3 Thus, the immature immune system of young calves likely moderates rather than prevents disease. This does not imply that young (< 8 months old) calves cannot respond to antigens; it simply means that the response to those antigens is weaker, slower, and easier to overcome than it will be when the immune system is mature.4 |
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