Evaluation of the efficacy of polymeric antigen BLSOmp31 formulated in a new cage-like particle adjuvant (ISPA YOLK) administered by parenteral or mucosal routes against Brucella ovis in rams

Brucella ovis (B. ovis) is the etiological agent of ram-contagious epididymitis, the leading cause of reproductive disorders in flocks worldwide. Although the attenuated B. melitensis Rev.1 strain gives heterologous protection against this pathogen, it has important disadvantages. Subunit vaccin...

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Main Authors:	Moran, Maria Celeste, Tammone Santos, Agostina, Dominguez, Paula, Moriones, Lucila, Nieto Farias, María Victoria, Maté, Laura, Garcia, Juan Agustin, Kuhn, Tobias, Paolicchi, Fernando, Fiorentino, María Andrea, Rodriguez, Marcelo Gaston, García, Jorge Pablo, Cacciato, Claudio Santiago, Goldbaum, Fernando Alberto, Zylberman, Vanesa, Pardo, Romina Paola, Foscaldi, Sabrina, Lützelschwab, Claudia María, Lupi, Giuliana, Marcipar, Ivan Santiago, Estein, Silvia Marcela
Format:	info:ar-repo/semantics/artículo
Language:	Inglés
Published:	Elsevier 2026
Subjects:	Enfermedad Bacteriana Epididimitis Infecciosa Ovina Brucella ovis Bacterial Diseases Ovine Infectious Epididymitis Epididimitis Contagiosa de Carneros Inmunógeno Antígeno Polimérico BLSOmp31
Online Access:	http://hdl.handle.net/20.500.12123/24988 https://doi.org/10.1016/j.vetimm.2025.110997