Antifungal activity of Parastrephia quadrangularis (Meyen) Cabrera extracts against Fusarium verticillioides

Fungi are cosmopolitan organisms that grow in and adapt to a vast number of substrates and environments, and that can cause diseases in humans and animals, as well as in crops. The vast area and diverse geographical characteristics of Argentina, with the consequent climatic diversity make the countr...

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Autores principales: Di Ciaccio, Lucí­a Soledad, Spotorno, Viviana Graciela, Córdoba Estévez, M.M., Rios, Dante Jose, Fortunato, Renee Hersilia, Salvat, Adriana Elisabeth
Formato: Artículo
Lenguaje:Inglés
Publicado: 2018
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12123/2152
https://onlinelibrary.wiley.com/doi/abs/10.1111/lam.12844
https://doi.org/10.1111/lam.12844
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author Di Ciaccio, Lucí­a Soledad
Spotorno, Viviana Graciela
Córdoba Estévez, M.M.
Rios, Dante Jose
Fortunato, Renee Hersilia
Salvat, Adriana Elisabeth
author_browse Córdoba Estévez, M.M.
Di Ciaccio, Lucí­a Soledad
Fortunato, Renee Hersilia
Rios, Dante Jose
Salvat, Adriana Elisabeth
Spotorno, Viviana Graciela
author_facet Di Ciaccio, Lucí­a Soledad
Spotorno, Viviana Graciela
Córdoba Estévez, M.M.
Rios, Dante Jose
Fortunato, Renee Hersilia
Salvat, Adriana Elisabeth
author_sort Di Ciaccio, Lucí­a Soledad
collection INTA Digital
description Fungi are cosmopolitan organisms that grow in and adapt to a vast number of substrates and environments, and that can cause diseases in humans and animals, as well as in crops. The vast area and diverse geographical characteristics of Argentina, with the consequent climatic diversity make the country an important source of biological resources suitable for the search of new compounds. The aim of the present study was to describe the antifungal activity of extracts of Parastrephia quadrangularis, a species from northern Argentina, against Fusarium verticillioides M7075. Bio‐guided fractionation and MS/MS studies were conducted to elucidate the chemical structure of active compounds. The extracts exhibited a minimum inhibitory concentration among 118·74 and 250 μg ml−1 and the differences between the treatments and the inoculum control was 12·5–16·5 mm, respectively, in colony growth. Moreover, hyphae treated with the extracts stained blue with Evans blue, showed alterations in permeability of plasma membranes. HLPC‐MS analysis of active fractions revealed the presence of p‐coumaroyloxitremetone, and a derivate structure for another compound is proposed.
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spelling INTA21522022-06-09T13:07:31Z Antifungal activity of Parastrephia quadrangularis (Meyen) Cabrera extracts against Fusarium verticillioides Di Ciaccio, Lucí­a Soledad Spotorno, Viviana Graciela Córdoba Estévez, M.M. Rios, Dante Jose Fortunato, Renee Hersilia Salvat, Adriana Elisabeth Fusarium Propiedades Antimicosicas Control de Enfermedades de Plantas Control Biológico Antifungal Properties Plant Disease Control Biological Control Parastrephia quadrangularis Fusarium Verticillioides Plantas Antifúngicas Fungi are cosmopolitan organisms that grow in and adapt to a vast number of substrates and environments, and that can cause diseases in humans and animals, as well as in crops. The vast area and diverse geographical characteristics of Argentina, with the consequent climatic diversity make the country an important source of biological resources suitable for the search of new compounds. The aim of the present study was to describe the antifungal activity of extracts of Parastrephia quadrangularis, a species from northern Argentina, against Fusarium verticillioides M7075. Bio‐guided fractionation and MS/MS studies were conducted to elucidate the chemical structure of active compounds. The extracts exhibited a minimum inhibitory concentration among 118·74 and 250 μg ml−1 and the differences between the treatments and the inoculum control was 12·5–16·5 mm, respectively, in colony growth. Moreover, hyphae treated with the extracts stained blue with Evans blue, showed alterations in permeability of plasma membranes. HLPC‐MS analysis of active fractions revealed the presence of p‐coumaroyloxitremetone, and a derivate structure for another compound is proposed. Instituto de Patobiología Fil: Di Ciaccio, Lucí­a Soledad. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina Fil: Spotorno, Viviana Graciela. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Recursos Biológicos; Argentina Fil: Córdoba Estévez, M.M. Instituto Nacional de Tecnología Industrial. Laboratorio de desarrollo analítico y control de procesos; Argentina Fil: Ríos, Dante José. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Abra Pampa. Agencia de Extensión Rural Abra Pampa; Argentina Fil: Fortunato, Renee Hersilia. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Recursos Biológicos; Argentina Fil: Salvat, Adriana Elisabeth. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patobiología; Argentina 2018-04-03T14:31:55Z 2018-04-03T14:31:55Z 2018-03 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/2152 https://onlinelibrary.wiley.com/doi/abs/10.1111/lam.12844 0266-8254 1472-765X https://doi.org/10.1111/lam.12844 eng info:eu-repo/semantics/restrictedAccess application/pdf Letters in applied microbiology 66 (3) : 244-251. (March 2018)
spellingShingle Fusarium
Propiedades Antimicosicas
Control de Enfermedades de Plantas
Control Biológico
Antifungal Properties
Plant Disease Control
Biological Control
Parastrephia quadrangularis
Fusarium Verticillioides
Plantas Antifúngicas
Di Ciaccio, Lucí­a Soledad
Spotorno, Viviana Graciela
Córdoba Estévez, M.M.
Rios, Dante Jose
Fortunato, Renee Hersilia
Salvat, Adriana Elisabeth
Antifungal activity of Parastrephia quadrangularis (Meyen) Cabrera extracts against Fusarium verticillioides
title Antifungal activity of Parastrephia quadrangularis (Meyen) Cabrera extracts against Fusarium verticillioides
title_full Antifungal activity of Parastrephia quadrangularis (Meyen) Cabrera extracts against Fusarium verticillioides
title_fullStr Antifungal activity of Parastrephia quadrangularis (Meyen) Cabrera extracts against Fusarium verticillioides
title_full_unstemmed Antifungal activity of Parastrephia quadrangularis (Meyen) Cabrera extracts against Fusarium verticillioides
title_short Antifungal activity of Parastrephia quadrangularis (Meyen) Cabrera extracts against Fusarium verticillioides
title_sort antifungal activity of parastrephia quadrangularis meyen cabrera extracts against fusarium verticillioides
topic Fusarium
Propiedades Antimicosicas
Control de Enfermedades de Plantas
Control Biológico
Antifungal Properties
Plant Disease Control
Biological Control
Parastrephia quadrangularis
Fusarium Verticillioides
Plantas Antifúngicas
url http://hdl.handle.net/20.500.12123/2152
https://onlinelibrary.wiley.com/doi/abs/10.1111/lam.12844
https://doi.org/10.1111/lam.12844
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