Targeting Leishmania infantum Mannosyl-oligosaccharide glucosidase with natural products : potential pH-dependent inhibition explored through computer-aided drug design
Visceral Leishmaniasis (VL) is a serious public health issue, documented in more than ninety countries, where an estimated 500,000 new cases emerge each year. Regardless of novel methodologies, advancements, and experimental interventions, therapeutic limitations, and drug resistance are still chall...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Artículo |
| Language: | Inglés |
| Published: |
Frontiers Media
2024
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.12123/20289 https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1403203/full https://doi.org/10.3389/fphar.2024.1403203 |
Similar Items: Targeting Leishmania infantum Mannosyl-oligosaccharide glucosidase with natural products : potential pH-dependent inhibition explored through computer-aided drug design
- Fallstudie av Leishmania infantum hos hundar, diagnostiska metoder, behandling och profylax
- Biochemical proxies indicate differences in soil C cycling induced by long-term tillage and residue management in a tropical agroecosystem
- Evaluación de la decocción de Hedeoma multiflora como potencial inhibidor de las enzimas alfa glucosidasa y Lipasa pancreática.
- Lactobacillus rhamnosus and Xylo-oligosaccharides improve meat quality and modulate the microbiota composition of Magang geese aged 22-50 days
- Antioxidant and starch-hydrolyzing enzymes inhibitory properties of Striga-resistant yellow-orange maize hybrids
- PsAA9A, a C1-specific AA9 lytic polysaccharide monooxygenase from the white-rot basidiomycete Pycnoporus sanguineus
