Analysis of scenarios to reduce the probability of acquiring hemolytic uremic syndrome associated with beef consumption
The objective of this study was to develop a quantitative microbial risk assessment (QMRA) model to evaluate potential risk mitigation strategies to reduce the probability of acquiring hemolytic uremic syndrome (HUS) associated with beef consumption in Argentina. Five scenarios were simulated to eva...
| Autores principales: | , , , , , , , |
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| Formato: | info:ar-repo/semantics/artículo |
| Lenguaje: | Inglés |
| Publicado: |
Sage Publications
2024
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| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12123/18804 https://journals.sagepub.com/doi/10.1177/10820132211046124 https://doi.org/10.1177/10820132211046124 |
| _version_ | 1855037921769291776 |
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| author | Costa, Magdalena Brusa, Victoria Padola, Nora Lía Etcheverría, Analía Inés Sampedro, Fernando Fernandez, Pablo S. Leotta, Gerardo Anibal Signorini Porchiett, Marcelo Lisandro |
| author_browse | Brusa, Victoria Costa, Magdalena Etcheverría, Analía Inés Fernandez, Pablo S. Leotta, Gerardo Anibal Padola, Nora Lía Sampedro, Fernando Signorini Porchiett, Marcelo Lisandro |
| author_facet | Costa, Magdalena Brusa, Victoria Padola, Nora Lía Etcheverría, Analía Inés Sampedro, Fernando Fernandez, Pablo S. Leotta, Gerardo Anibal Signorini Porchiett, Marcelo Lisandro |
| author_sort | Costa, Magdalena |
| collection | INTA Digital |
| description | The objective of this study was to develop a quantitative microbial risk assessment (QMRA) model to evaluate potential risk mitigation strategies to reduce the probability of acquiring hemolytic uremic syndrome (HUS) associated with beef consumption in Argentina. Five scenarios were simulated to evaluate the effect of interventions on the probability of acquiring HUS from Shiga toxin-producing Escherichia coli (STEC)-contaminated ground beef and commercial hamburger consumption. These control strategies were chosen based on previous results of the sensitivity analysis of a baseline QMRA model. The application of improvement actions in abattoirs not applying Hazard Analysis and Critical Control Points (HACCP) for STEC would result 7.6 times lower in the probability that consumers acquired HUS from ground beef consumption, while the implementation of improvements in butcher shops would lead to a smaller reduction. In abattoirs applying HACCP for STEC, the risk of acquiring HUS from commercial hamburger consumption was significantly reduced. Treatment with 2% lactic acid, hot water and irradiation reduced 4.5, 3.5 and 93.1 times the risk of HUS, respectively. The most efficient interventions, in terms of case reduction, being those that are applied in the initial stages of the meat chain. |
| format | info:ar-repo/semantics/artículo |
| id | INTA18804 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2024 |
| publishDateRange | 2024 |
| publishDateSort | 2024 |
| publisher | Sage Publications |
| publisherStr | Sage Publications |
| record_format | dspace |
| spelling | INTA188042024-08-05T13:42:51Z Analysis of scenarios to reduce the probability of acquiring hemolytic uremic syndrome associated with beef consumption Costa, Magdalena Brusa, Victoria Padola, Nora Lía Etcheverría, Analía Inés Sampedro, Fernando Fernandez, Pablo S. Leotta, Gerardo Anibal Signorini Porchiett, Marcelo Lisandro Carne de Res Enfermedades Humanas Anemia Hemolítica Evaluación de Riesgos Intoxicación Alimentaría Beef Escherichia coli Human Diseases Haemolytic Anaemia Risk Assessment Food Poisoning Síndrome Urémico Hemolítico Haemolytic Uremic Syndrome The objective of this study was to develop a quantitative microbial risk assessment (QMRA) model to evaluate potential risk mitigation strategies to reduce the probability of acquiring hemolytic uremic syndrome (HUS) associated with beef consumption in Argentina. Five scenarios were simulated to evaluate the effect of interventions on the probability of acquiring HUS from Shiga toxin-producing Escherichia coli (STEC)-contaminated ground beef and commercial hamburger consumption. These control strategies were chosen based on previous results of the sensitivity analysis of a baseline QMRA model. The application of improvement actions in abattoirs not applying Hazard Analysis and Critical Control Points (HACCP) for STEC would result 7.6 times lower in the probability that consumers acquired HUS from ground beef consumption, while the implementation of improvements in butcher shops would lead to a smaller reduction. In abattoirs applying HACCP for STEC, the risk of acquiring HUS from commercial hamburger consumption was significantly reduced. Treatment with 2% lactic acid, hot water and irradiation reduced 4.5, 3.5 and 93.1 times the risk of HUS, respectively. The most efficient interventions, in terms of case reduction, being those that are applied in the initial stages of the meat chain. EEA Rafaela Fil: Costa, Magdalena. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout"; Argentina Fil: Costa, Magdalena. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout"; Argentina Fil: Brusa, Victoria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout"; Argentina Fil: Brusa, Victoria. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout"; Argentina Fil: Padola, Nora Lía. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil; Argentina Fil: Padola, Nora Lía. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil; Argentina Fil: Padola, Nora Lía. Provincia de Buenos Aires. Comisión de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina Fil: Etcheverría, Analía Inés. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil; Argentina Fil: Etcheverría, Analía Inés. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil; Argentina Fil: Etcheverría, Analía Inés. Provincia de Buenos Aires. Comisión de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina Fil: Sampedro, Fernando. University of Minnesota. School of Public Health. Environmental Health Sciences Division; Estados Unidos Fil: Fernandez, Pablo S. Universidad Politécnica de Cartagena. Escuela Técnica Superior de Ingeniería Agronómica; España Fil: Leotta, Gerardo Anibal. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico CONICET- La Plata. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout"; Argentina Fil: Leotta, Gerardo Aniba. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias. Instituto de Genética Veterinaria "Ing. Fernando Noel Dulout"; Argentina Fil: Signorini, Marcelo. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela. Instituto de Investigación de la Cadena Láctea (IdICaL); Argentina. Fil: Signorini, Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación de la Cadena Láctea (IdICaL); Argentina. 2024-08-05T13:38:53Z 2024-08-05T13:38:53Z 2021 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/18804 https://journals.sagepub.com/doi/10.1177/10820132211046124 1082-0132 https://doi.org/10.1177/10820132211046124 eng info:eu-repo/semantics/restrictedAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Sage Publications Food Science and Technology International 28 (7) : 613-621. (2021) |
| spellingShingle | Carne de Res Enfermedades Humanas Anemia Hemolítica Evaluación de Riesgos Intoxicación Alimentaría Beef Escherichia coli Human Diseases Haemolytic Anaemia Risk Assessment Food Poisoning Síndrome Urémico Hemolítico Haemolytic Uremic Syndrome Costa, Magdalena Brusa, Victoria Padola, Nora Lía Etcheverría, Analía Inés Sampedro, Fernando Fernandez, Pablo S. Leotta, Gerardo Anibal Signorini Porchiett, Marcelo Lisandro Analysis of scenarios to reduce the probability of acquiring hemolytic uremic syndrome associated with beef consumption |
| title | Analysis of scenarios to reduce the probability of acquiring hemolytic uremic syndrome associated with beef consumption |
| title_full | Analysis of scenarios to reduce the probability of acquiring hemolytic uremic syndrome associated with beef consumption |
| title_fullStr | Analysis of scenarios to reduce the probability of acquiring hemolytic uremic syndrome associated with beef consumption |
| title_full_unstemmed | Analysis of scenarios to reduce the probability of acquiring hemolytic uremic syndrome associated with beef consumption |
| title_short | Analysis of scenarios to reduce the probability of acquiring hemolytic uremic syndrome associated with beef consumption |
| title_sort | analysis of scenarios to reduce the probability of acquiring hemolytic uremic syndrome associated with beef consumption |
| topic | Carne de Res Enfermedades Humanas Anemia Hemolítica Evaluación de Riesgos Intoxicación Alimentaría Beef Escherichia coli Human Diseases Haemolytic Anaemia Risk Assessment Food Poisoning Síndrome Urémico Hemolítico Haemolytic Uremic Syndrome |
| url | http://hdl.handle.net/20.500.12123/18804 https://journals.sagepub.com/doi/10.1177/10820132211046124 https://doi.org/10.1177/10820132211046124 |
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