Development of a platform process for the production and purification of single‐domain antibodies

Single-domain antibodies (sdAbs) offer the affinity and therapeutic value of conventional antibodies, with increased stability and solubility. Unlike conventional antibodies, however, sdAbs do not benefit from a platform manufacturing process. While successful production of a variety of sdAbs has be...

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Bibliographic Details

Main Authors:	Crowell, Laura E., Goodwine, Chaz, Sosa Holt, Carla Solange, Rocha, Lucía Alejandra, Vega, Celina Guadalupe, Rodriguez-Aponte, Sergio A., Dalvie, Neil C., Tracey, Mary Kate, Puntel, Mariana, Wigdorovitz, Andres, Parreño, Gladys, Love, Kerry R., Cramer, Steven M., Love, J. Christopher
Format:	info:ar-repo/semantics/artículo
Language:	Inglés
Published:	Wiley 2023
Subjects:	Pichia pastoris Purificación Anticuerpos Purification Antibodies Komagataella phaffii
Online Access:	http://hdl.handle.net/20.500.12123/15527 https://onlinelibrary.wiley.com/doi/10.1002/bit.27724 https://doi.org/10.1002/bit.27724