Acinetobacter baumannii and Its relationship to carbapenem resistance : a meta-analysis
Infections by antibiotic-resistant bacteria are a significant and complex global health issue. In this context, Acinetobacter baumannii is particularly important because of its ability to withstand treatments by β-lactams, such as carbapenem. The objective of this work was to investigate, through sy...
| Autores principales: | , , , , |
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| Formato: | Artículo |
| Lenguaje: | Inglés |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12123/12648 https://www.mdpi.com/2674-1334/1/2/10 https://doi.org/10.3390/bacteria1020010 |
| _version_ | 1855485019834810368 |
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| author | Rodrigues, Diego Lucas Neres Costa, Francielly Morais Rodrigues da Marques Da Silva, Wanderson Aburjaile, Flavia Azevedo, Vasco |
| author_browse | Aburjaile, Flavia Azevedo, Vasco Costa, Francielly Morais Rodrigues da Marques Da Silva, Wanderson Rodrigues, Diego Lucas Neres |
| author_facet | Rodrigues, Diego Lucas Neres Costa, Francielly Morais Rodrigues da Marques Da Silva, Wanderson Aburjaile, Flavia Azevedo, Vasco |
| author_sort | Rodrigues, Diego Lucas Neres |
| collection | INTA Digital |
| description | Infections by antibiotic-resistant bacteria are a significant and complex global health issue. In this context, Acinetobacter baumannii is particularly important because of its ability to withstand treatments by β-lactams, such as carbapenem. The objective of this work was to investigate, through systematic analysis and meta-analysis, the chance of resistance to carbapenem in A. baumannii strains. For this, a search was conducted for the PubMed and Cochrane databases based on the keywords: “Acinetobacter baumannii” AND “beta-lactam” OR “penicillin” OR “cephalosporin” OR “cephamycin” OR “carbapenem” OR “monobactam”. The initial search resulted in a total of 90,475 articles. It was filtered based on eligibility criteria, and eight articles were selected for analysis. An odds ratio value equivalent to 3.55 was obtained, indicating a high chance of resistance to the carbapenem of strains of the species. Therefore, it is supposed that A. baumannii infection cases have a high probability of not responding adequately to treatments based on carbapenem. |
| format | Artículo |
| id | INTA12648 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | MDPI |
| publisherStr | MDPI |
| record_format | dspace |
| spelling | INTA126482022-08-22T12:40:13Z Acinetobacter baumannii and Its relationship to carbapenem resistance : a meta-analysis Rodrigues, Diego Lucas Neres Costa, Francielly Morais Rodrigues da Marques Da Silva, Wanderson Aburjaile, Flavia Azevedo, Vasco Infection Acinetobacter Resistance to Antibiotics Infección Resistencia a los Antibióticos Acinetobacter baumannii Carbapenem Infections by antibiotic-resistant bacteria are a significant and complex global health issue. In this context, Acinetobacter baumannii is particularly important because of its ability to withstand treatments by β-lactams, such as carbapenem. The objective of this work was to investigate, through systematic analysis and meta-analysis, the chance of resistance to carbapenem in A. baumannii strains. For this, a search was conducted for the PubMed and Cochrane databases based on the keywords: “Acinetobacter baumannii” AND “beta-lactam” OR “penicillin” OR “cephalosporin” OR “cephamycin” OR “carbapenem” OR “monobactam”. The initial search resulted in a total of 90,475 articles. It was filtered based on eligibility criteria, and eight articles were selected for analysis. An odds ratio value equivalent to 3.55 was obtained, indicating a high chance of resistance to the carbapenem of strains of the species. Therefore, it is supposed that A. baumannii infection cases have a high probability of not responding adequately to treatments based on carbapenem. Instituto de Biotecnología Fil: Rodrigues, Diego Lucas Neres. Universidade Federal de Minas Gerais. Laboratory of Cellular and Molecular Genetics; Brasil Fil: Rodrigues da Costa, Francielly Morais. Universidade Federal de Minas Gerais. Laboratory of Cellular and Molecular Genetics; Brasil Fil: Marques Da Silva, Wanderson. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Agrobiotecnología y Biología Molecular; Argentina Fil: Marques Da Silva, Wanderson. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Aburjaile, Flavia. Universidade Federal de Minas Gerais. Veterinary School. Preventive Veterinary Medicine Department; Brasil Fil: Azevedo, Vasco. Universidade Federal de Minas Gerais. Laboratory of Cellular and Molecular Genetics; Brasil 2022-08-22T12:33:05Z 2022-08-22T12:33:05Z 2022-05 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/12648 https://www.mdpi.com/2674-1334/1/2/10 2674-1334 https://doi.org/10.3390/bacteria1020010 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf MDPI Bacteria 1 (2) : 112-120 (June 2022) |
| spellingShingle | Infection Acinetobacter Resistance to Antibiotics Infección Resistencia a los Antibióticos Acinetobacter baumannii Carbapenem Rodrigues, Diego Lucas Neres Costa, Francielly Morais Rodrigues da Marques Da Silva, Wanderson Aburjaile, Flavia Azevedo, Vasco Acinetobacter baumannii and Its relationship to carbapenem resistance : a meta-analysis |
| title | Acinetobacter baumannii and Its relationship to carbapenem resistance : a meta-analysis |
| title_full | Acinetobacter baumannii and Its relationship to carbapenem resistance : a meta-analysis |
| title_fullStr | Acinetobacter baumannii and Its relationship to carbapenem resistance : a meta-analysis |
| title_full_unstemmed | Acinetobacter baumannii and Its relationship to carbapenem resistance : a meta-analysis |
| title_short | Acinetobacter baumannii and Its relationship to carbapenem resistance : a meta-analysis |
| title_sort | acinetobacter baumannii and its relationship to carbapenem resistance a meta analysis |
| topic | Infection Acinetobacter Resistance to Antibiotics Infección Resistencia a los Antibióticos Acinetobacter baumannii Carbapenem |
| url | http://hdl.handle.net/20.500.12123/12648 https://www.mdpi.com/2674-1334/1/2/10 https://doi.org/10.3390/bacteria1020010 |
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