Alfalfa dwarf cytorhabdovirus P protein is a local and systemic RNA silencing supressor which inhibis program med RISC activity and prevents transitive amplification of RNA silencing
Plants employ RNA silencing as an innate defense mechanism against viruses. As a counter-defense, plant viruses have evolved to express RNA silencing suppressor proteins (RSS), which target one or more steps of the silencing pathway. In this study, we show that the phosphoprotein (P) encoded by th...
| Autores principales: | , , |
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| Formato: | Artículo |
| Lenguaje: | Inglés |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12123/1253 http://www.sciencedirect.com/science/article/pii/S0168170216303987?via%3Dihub https://doi.org/10.1016/j.virusres.2016.08.008 |
| _version_ | 1855482855964016640 |
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| author | Bejerman, Nicolas Esteban Mann, Krin S. Dietzgen, Ralf Georg |
| author_browse | Bejerman, Nicolas Esteban Dietzgen, Ralf Georg Mann, Krin S. |
| author_facet | Bejerman, Nicolas Esteban Mann, Krin S. Dietzgen, Ralf Georg |
| author_sort | Bejerman, Nicolas Esteban |
| collection | INTA Digital |
| description | Plants employ RNA silencing as an innate defense mechanism against viruses. As a counter-defense, plant
viruses have evolved to express RNA silencing suppressor proteins (RSS), which target one or more steps
of the silencing pathway. In this study, we show that the phosphoprotein (P) encoded by the negativesense
RNA virus alfalfa dwarf virus (ADV), a species of the genus Cytorhabdovirus, family Rhabdoviridae,
is a suppressor of RNA silencing. ADV P has a relatively weak local RSS activity, and does not prevent
siRNA accumulation. |
| format | Artículo |
| id | INTA1253 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2017 |
| publishDateRange | 2017 |
| publishDateSort | 2017 |
| record_format | dspace |
| spelling | INTA12532019-03-22T14:04:08Z Alfalfa dwarf cytorhabdovirus P protein is a local and systemic RNA silencing supressor which inhibis program med RISC activity and prevents transitive amplification of RNA silencing Bejerman, Nicolas Esteban Mann, Krin S. Dietzgen, Ralf Georg Enfermedades de las Plantas Medicago Sativa Virus de las Plantas Secuencia de ARN Plant Diseases Plant Viruses RNA Sequence RNA Viruses Alfalfa Plants employ RNA silencing as an innate defense mechanism against viruses. As a counter-defense, plant viruses have evolved to express RNA silencing suppressor proteins (RSS), which target one or more steps of the silencing pathway. In this study, we show that the phosphoprotein (P) encoded by the negativesense RNA virus alfalfa dwarf virus (ADV), a species of the genus Cytorhabdovirus, family Rhabdoviridae, is a suppressor of RNA silencing. ADV P has a relatively weak local RSS activity, and does not prevent siRNA accumulation. Inst. Patología Vegetal Fil: Bejerman, Nicolas Esteban. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patología Vegetal; Argentina Fil: Mann, Krin S. Agriculture and Agri-Food Canada, Summerland Research and Development Centre; Canadá Dietzgen,Ralf Georg. University of Queensland. Queensland Alliance for Agriculture and Food Innovation; Australia 2017-09-19T15:03:22Z 2017-09-19T15:03:22Z 2016 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion http://hdl.handle.net/20.500.12123/1253 http://www.sciencedirect.com/science/article/pii/S0168170216303987?via%3Dihub 0168-1702 https://doi.org/10.1016/j.virusres.2016.08.008 eng info:eu-repo/semantics/restrictedAccess application/pdf Virus research 224 :19-28. (September 2016) |
| spellingShingle | Enfermedades de las Plantas Medicago Sativa Virus de las Plantas Secuencia de ARN Plant Diseases Plant Viruses RNA Sequence RNA Viruses Alfalfa Bejerman, Nicolas Esteban Mann, Krin S. Dietzgen, Ralf Georg Alfalfa dwarf cytorhabdovirus P protein is a local and systemic RNA silencing supressor which inhibis program med RISC activity and prevents transitive amplification of RNA silencing |
| title | Alfalfa dwarf cytorhabdovirus P protein is a local and systemic RNA silencing supressor which inhibis program med RISC activity and prevents transitive amplification of RNA silencing |
| title_full | Alfalfa dwarf cytorhabdovirus P protein is a local and systemic RNA silencing supressor which inhibis program med RISC activity and prevents transitive amplification of RNA silencing |
| title_fullStr | Alfalfa dwarf cytorhabdovirus P protein is a local and systemic RNA silencing supressor which inhibis program med RISC activity and prevents transitive amplification of RNA silencing |
| title_full_unstemmed | Alfalfa dwarf cytorhabdovirus P protein is a local and systemic RNA silencing supressor which inhibis program med RISC activity and prevents transitive amplification of RNA silencing |
| title_short | Alfalfa dwarf cytorhabdovirus P protein is a local and systemic RNA silencing supressor which inhibis program med RISC activity and prevents transitive amplification of RNA silencing |
| title_sort | alfalfa dwarf cytorhabdovirus p protein is a local and systemic rna silencing supressor which inhibis program med risc activity and prevents transitive amplification of rna silencing |
| topic | Enfermedades de las Plantas Medicago Sativa Virus de las Plantas Secuencia de ARN Plant Diseases Plant Viruses RNA Sequence RNA Viruses Alfalfa |
| url | http://hdl.handle.net/20.500.12123/1253 http://www.sciencedirect.com/science/article/pii/S0168170216303987?via%3Dihub https://doi.org/10.1016/j.virusres.2016.08.008 |
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