Differential mRNA accumulation upon early arabidopsis thaliana infection with ORMV and TMV-Cg Is associated with distinct endogenous small RNAs Level

Small RNAs (sRNAs) play important roles in plant development and host-pathogen interactions. Several studies have highlighted the relationship between viral infections, endogenous sRNA accumulation and transcriptional changes associated with symptoms. However, few studies have described a global...

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Autores principales: Zavallo, Diego, Debat, Humberto Julio, Conti, Gabriela, Manacorda, Carlos Augusto, Rodriguez, Maria Cecilia, Asurmendi, Sebastian
Formato: info:ar-repo/semantics/artículo
Lenguaje:Inglés
Publicado: 2017
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12123/1232
http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0134719&type=printable
https://doi.org/10.1371/journal.pone.0134719
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author Zavallo, Diego
Debat, Humberto Julio
Conti, Gabriela
Manacorda, Carlos Augusto
Rodriguez, Maria Cecilia
Asurmendi, Sebastian
author_browse Asurmendi, Sebastian
Conti, Gabriela
Debat, Humberto Julio
Manacorda, Carlos Augusto
Rodriguez, Maria Cecilia
Zavallo, Diego
author_facet Zavallo, Diego
Debat, Humberto Julio
Conti, Gabriela
Manacorda, Carlos Augusto
Rodriguez, Maria Cecilia
Asurmendi, Sebastian
author_sort Zavallo, Diego
collection INTA Digital
description Small RNAs (sRNAs) play important roles in plant development and host-pathogen interactions. Several studies have highlighted the relationship between viral infections, endogenous sRNA accumulation and transcriptional changes associated with symptoms. However, few studies have described a global analysis of endogenous sRNAs by comparing related viruses at early stages of infection, especially before viral accumulation reaches systemic tissues. An sRNA high-throughput sequencing of Arabidopsis thaliana leaf samples infected either with Oilseed rape mosaic virus (ORMV) or crucifer-infecting Tobacco mosaic virus (TMV-Cg) with slightly different symptomatology at two early stages of infection (2 and 4dpi) was performed. At early stages, both viral infections strongly alter the patterns of several types of endogenous sRNA species in distal tissues with no virus accumulation suggesting a systemic signaling process foregoing to virus spread. A correlation between sRNAs derived from protein coding genes and the associated mRNA transcripts was also detected, indicating that an unknown recursive mechanism is involved in a regulatory circuit encompassing this sRNA/mRNA equilibrium. This work represents the initial step in uncovering how differential accumulation of endogenous sRNAs contributes to explain the massive alteration of the transcriptome associated with plant-virus interactions
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institution Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina)
language Inglés
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publishDateRange 2017
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spelling INTA12322017-11-28T12:42:11Z Differential mRNA accumulation upon early arabidopsis thaliana infection with ORMV and TMV-Cg Is associated with distinct endogenous small RNAs Level Zavallo, Diego Debat, Humberto Julio Conti, Gabriela Manacorda, Carlos Augusto Rodriguez, Maria Cecilia Asurmendi, Sebastian Arabidopsis Thaliana ARN Virus de las Plantas Genética Genetics RNA Plant Viruses SRNA ORMV Small RNAs (sRNAs) play important roles in plant development and host-pathogen interactions. Several studies have highlighted the relationship between viral infections, endogenous sRNA accumulation and transcriptional changes associated with symptoms. However, few studies have described a global analysis of endogenous sRNAs by comparing related viruses at early stages of infection, especially before viral accumulation reaches systemic tissues. An sRNA high-throughput sequencing of Arabidopsis thaliana leaf samples infected either with Oilseed rape mosaic virus (ORMV) or crucifer-infecting Tobacco mosaic virus (TMV-Cg) with slightly different symptomatology at two early stages of infection (2 and 4dpi) was performed. At early stages, both viral infections strongly alter the patterns of several types of endogenous sRNA species in distal tissues with no virus accumulation suggesting a systemic signaling process foregoing to virus spread. A correlation between sRNAs derived from protein coding genes and the associated mRNA transcripts was also detected, indicating that an unknown recursive mechanism is involved in a regulatory circuit encompassing this sRNA/mRNA equilibrium. This work represents the initial step in uncovering how differential accumulation of endogenous sRNAs contributes to explain the massive alteration of the transcriptome associated with plant-virus interactions Fil: Zavallo, Diego. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Debat, Humberto Julio. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Patología Vegetal; Argentina Fil: Conti, Gabriela. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Manacorda, Carlos Augusto. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina Fil: Rodriguez, Maria Cecilia. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina Fil: Asurmendi, Sebastian. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Biotecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina 2017-09-15T18:01:26Z 2017-09-15T18:01:26Z 2015-08-03 info:ar-repo/semantics/artículo info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/1232 http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0134719&type=printable 1932-6203 https://doi.org/10.1371/journal.pone.0134719 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Plos one 10 (8) : e0134719. (2015).
spellingShingle Arabidopsis Thaliana
ARN
Virus de las Plantas
Genética
Genetics
RNA
Plant Viruses
SRNA
ORMV
Zavallo, Diego
Debat, Humberto Julio
Conti, Gabriela
Manacorda, Carlos Augusto
Rodriguez, Maria Cecilia
Asurmendi, Sebastian
Differential mRNA accumulation upon early arabidopsis thaliana infection with ORMV and TMV-Cg Is associated with distinct endogenous small RNAs Level
title Differential mRNA accumulation upon early arabidopsis thaliana infection with ORMV and TMV-Cg Is associated with distinct endogenous small RNAs Level
title_full Differential mRNA accumulation upon early arabidopsis thaliana infection with ORMV and TMV-Cg Is associated with distinct endogenous small RNAs Level
title_fullStr Differential mRNA accumulation upon early arabidopsis thaliana infection with ORMV and TMV-Cg Is associated with distinct endogenous small RNAs Level
title_full_unstemmed Differential mRNA accumulation upon early arabidopsis thaliana infection with ORMV and TMV-Cg Is associated with distinct endogenous small RNAs Level
title_short Differential mRNA accumulation upon early arabidopsis thaliana infection with ORMV and TMV-Cg Is associated with distinct endogenous small RNAs Level
title_sort differential mrna accumulation upon early arabidopsis thaliana infection with ormv and tmv cg is associated with distinct endogenous small rnas level
topic Arabidopsis Thaliana
ARN
Virus de las Plantas
Genética
Genetics
RNA
Plant Viruses
SRNA
ORMV
url http://hdl.handle.net/20.500.12123/1232
http://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0134719&type=printable
https://doi.org/10.1371/journal.pone.0134719
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