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Metabolic profile of mycobacterium smegmatis reveals Mce4 proteins are relevant for cell wall lipid homeostasis

Introduction The Mce proteins are encoded in a variable number of operons (from one to eight) in all Mycobacterium species. A role in the transport of host and mycobacterial lipids has been demonstrated for some Mce proteins in the pathogen Mycobacterium tuberculosis but little is known about these...

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Main Authors: Santangelo, María De La Paz, Heuberger, Adam, Blanco, Federico Carlos, Forrellad, Marina Andrea, Taibo, Catalina Beatriz, Klepp, Laura Ines, Sabio y Garcia, Julia Veronica, Nikel, Pablo I., Jackson, Mary, Bigi, Fabiana
Format: info:eu-repo/semantics/article
Language:Inglés
Published: 2017
Subjects:
Genética
Metabolismo
Mycobacterium
Homeostasis
Genetics
Metabolism
Perfil Metabólico
Mycobacterium Smegmatis
Online Access:http://hdl.handle.net/20.500.12123/1193
https://doi.org/10.1007/s11306-016-1035-4
Summary:Introduction The Mce proteins are encoded in a variable number of operons (from one to eight) in all Mycobacterium species. A role in the transport of host and mycobacterial lipids has been demonstrated for some Mce proteins in the pathogen Mycobacterium tuberculosis but little is known about these proteins in Mycobacterium smegmatis, a soil dweller species. Objective To investigate the role of Mce proteins in M. smegmatis.

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