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Metabolic profile of mycobacterium smegmatis reveals Mce4 proteins are relevant for cell wall lipid homeostasis

Introduction The Mce proteins are encoded in a variable number of operons (from one to eight) in all Mycobacterium species. A role in the transport of host and mycobacterial lipids has been demonstrated for some Mce proteins in the pathogen Mycobacterium tuberculosis but little is known about these...

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Autores principales: Santangelo, María De La Paz, Heuberger, Adam, Blanco, Federico Carlos, Forrellad, Marina Andrea, Taibo, Catalina Beatriz, Klepp, Laura Ines, Sabio y Garcia, Julia Veronica, Nikel, Pablo I., Jackson, Mary, Bigi, Fabiana
Formato: info:eu-repo/semantics/article
Lenguaje:Inglés
Publicado: 2017
Materias:
Genética
Metabolismo
Mycobacterium
Homeostasis
Genetics
Metabolism
Perfil Metabólico
Mycobacterium Smegmatis
Acceso en línea:http://hdl.handle.net/20.500.12123/1193
https://doi.org/10.1007/s11306-016-1035-4
Sumario:Introduction The Mce proteins are encoded in a variable number of operons (from one to eight) in all Mycobacterium species. A role in the transport of host and mycobacterial lipids has been demonstrated for some Mce proteins in the pathogen Mycobacterium tuberculosis but little is known about these proteins in Mycobacterium smegmatis, a soil dweller species. Objective To investigate the role of Mce proteins in M. smegmatis.

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