Babesia bovis AMA-1, MSA-2c and RAP-1 contain conserved B and T-cell epitopes, which generate neutralizing antibodies and a long-lasting Th1 immune response in vaccinated cattle

Vaccines against bovine babesiosis must, ideally, induce a humoral immune response characterized by neutralizing antibodies against conserved epitopes and a cellular Th1 immune response. In Babesia bovis, proteins such as AMA-1, MSA-2c, and RAP-1 have been characterized and antibodies against these...

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Bibliographic Details

Main Authors:	Hidalgo-Ruiz, Mario, Mejia-López, Susana, Pérez-Serrano, Rosa M., Zaldívar-Lelo de Larrea, Guadalupe, Ganzinelli, Sabrina Belen, Florin-Christensen, Monica, Suarez, Carlos Esteban, Hernández-Ortiz, Rubén, Mercado-Uriostegui, Miguel A., Rodríguez-Torres, Angelina, Carvajal-Gamez, Bertha I., Camacho-Nuez, Minerva, Wilkowsky, Silvina Elizabeth, Mosqueda, Juan
Format:	Artículo
Language:	Inglés
Published:	Elsevier 2022
Subjects:	Babesia bovis Linfocitos-t Interferonas Anticuerpos Respuesta Inmunológica Neutralización T-lymphocytes Interferons Antibodies Immune Response Neutralization T-cell Células-t
Online Access:	http://hdl.handle.net/20.500.12123/11574 https://www.sciencedirect.com/science/article/pii/S0264410X22000494 https://doi.org/10.1016/j.vaccine.2022.01.023