Phylogenetic and structural analyses of equine rotaviruses : three possible geographically related lineages
The structural analyses revealed that the aa substitutions in VP7 are in the antigenic sites and in the VP7:VP6 interaction region. In accordance, most of the aa changes in VP6 are in the top of the protein involving antigenic and VP7:VP6 interaction sites. Interestingly, the structural analyses o...
| Autores principales: | , , |
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| Formato: | Artículo |
| Lenguaje: | Inglés |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12123/1015 http://www.j-evs.com/article/S0737-0806(16)00086-1/pdf http://dx.doi.org/10.1016/j.jevs.2016.02.055 |
| _version_ | 1855482803607568384 |
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| author | Miño, Samuel Parreño, Viviana Barrandeguy, Maria Edith |
| author_browse | Barrandeguy, Maria Edith Miño, Samuel Parreño, Viviana |
| author_facet | Miño, Samuel Parreño, Viviana Barrandeguy, Maria Edith |
| author_sort | Miño, Samuel |
| collection | INTA Digital |
| description | The structural analyses revealed that the aa substitutions
in VP7 are in the antigenic sites and in the VP7:VP6
interaction region. In accordance, most of the aa changes in VP6 are in the top of the protein involving antigenic and VP7:VP6 interaction sites. Interestingly, the structural analyses of VP8* showed a few aa differences in the antigenic sites and, all equine P[12] shown the same conserved aa sequence in VP8* pocket, only observed in P[12] genotype. Our study suggest the existence of geographically related equine RVA lineages and,
describe the aa configuration of the VP8* pocket. |
| format | Artículo |
| id | INTA1015 |
| institution | Instituto Nacional de Tecnología Agropecuaria (INTA -Argentina) |
| language | Inglés |
| publishDate | 2017 |
| publishDateRange | 2017 |
| publishDateSort | 2017 |
| record_format | dspace |
| spelling | INTA10152017-12-18T17:26:04Z Phylogenetic and structural analyses of equine rotaviruses : three possible geographically related lineages Miño, Samuel Parreño, Viviana Barrandeguy, Maria Edith Animal Diseases Horses Genetics Enfermedades de los Animales Rotavirus Caballos Genética The structural analyses revealed that the aa substitutions in VP7 are in the antigenic sites and in the VP7:VP6 interaction region. In accordance, most of the aa changes in VP6 are in the top of the protein involving antigenic and VP7:VP6 interaction sites. Interestingly, the structural analyses of VP8* showed a few aa differences in the antigenic sites and, all equine P[12] shown the same conserved aa sequence in VP8* pocket, only observed in P[12] genotype. Our study suggest the existence of geographically related equine RVA lineages and, describe the aa configuration of the VP8* pocket. Inst.de Virología Fil: Miño, Samuel. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina Fil: Parreño, Viviana. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina Fil: Barrandeguy, Maria Edith. Instituto Nacional de Tecnología Agropecuaria (INTA). Instituto de Virología; Argentina. Universidad del Salvador. Escuela de Veterinaria; Argentina 2017-08-23T13:39:08Z 2017-08-23T13:39:08Z 2016 info:eu-repo/semantics/article info:ar-repo/semantics/artículo info:eu-repo/semantics/publishedVersion http://hdl.handle.net/20.500.12123/1015 http://www.j-evs.com/article/S0737-0806(16)00086-1/pdf 0737-0806 http://dx.doi.org/10.1016/j.jevs.2016.02.055 eng info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/4.0/ Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) application/pdf Journal of equine veterinary science 39 : S23eS25 |
| spellingShingle | Animal Diseases Horses Genetics Enfermedades de los Animales Rotavirus Caballos Genética Miño, Samuel Parreño, Viviana Barrandeguy, Maria Edith Phylogenetic and structural analyses of equine rotaviruses : three possible geographically related lineages |
| title | Phylogenetic and structural analyses of equine rotaviruses : three possible geographically related lineages |
| title_full | Phylogenetic and structural analyses of equine rotaviruses : three possible geographically related lineages |
| title_fullStr | Phylogenetic and structural analyses of equine rotaviruses : three possible geographically related lineages |
| title_full_unstemmed | Phylogenetic and structural analyses of equine rotaviruses : three possible geographically related lineages |
| title_short | Phylogenetic and structural analyses of equine rotaviruses : three possible geographically related lineages |
| title_sort | phylogenetic and structural analyses of equine rotaviruses three possible geographically related lineages |
| topic | Animal Diseases Horses Genetics Enfermedades de los Animales Rotavirus Caballos Genética |
| url | http://hdl.handle.net/20.500.12123/1015 http://www.j-evs.com/article/S0737-0806(16)00086-1/pdf http://dx.doi.org/10.1016/j.jevs.2016.02.055 |
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