Baculovirus transduction in mammalian cells is affected by the production of type I and III interferons, which is mediated mainly by the cGAS-STING pathway
The baculovirus Autographa californica multiple nucleopolyhedrovirus is an insect virus with a circular double-stranded DNA genome, which, among other multiple biotechnological applications, is used as an expression vector for gene delivery in mammalian cells. Nevertheless, the nonspecific immune re...
| Main Authors: | , , , , , |
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| Format: | Artículo |
| Language: | Inglés |
| Published: |
American Society for Microbiology
2021
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.12123/10117 https://journals.asm.org/doi/10.1128/JVI.01555-20 https://doi.org/10.1128/JVI.01555-20 |
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