Baculovirus transduction in mammalian cells is affected by the production of type I and III interferons, which is mediated mainly by the cGAS-STING pathway

The baculovirus Autographa californica multiple nucleopolyhedrovirus is an insect virus with a circular double-stranded DNA genome, which, among other multiple biotechnological applications, is used as an expression vector for gene delivery in mammalian cells. Nevertheless, the nonspecific immune re...

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Detalles Bibliográficos
Autores principales: Amalfi, Sabrina, Molina, Guido Nicolas, Bevacqua, Romina Jimena, Lopez, Maria Gabriela, Taboga, Oscar Alberto, Alfonso, Victoria
Formato: info:ar-repo/semantics/artículo
Lenguaje:Inglés
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:http://hdl.handle.net/20.500.12123/10117
https://journals.asm.org/doi/10.1128/JVI.01555-20
https://doi.org/10.1128/JVI.01555-20

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