Leveraging the Medicines for Malaria Venture malaria and pathogen boxes to discover chemical inhibitors of East Coast fever
Chemotherapy of East Coast fever, a lymphoproliferative cancer-like disease of cattle causing significant economic losses in Africa, is largely dependent on the use of buparvaquone, a drug that was developed in the late 1980's. The disease is caused by the tick-borne protozoan pathogen Theileria par...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
Elsevier
2019
|
| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/99526 |
Ejemplares similares: Leveraging the Medicines for Malaria Venture malaria and pathogen boxes to discover chemical inhibitors of East Coast fever
- Proteomics of Theileria parva sporozoites
- The biology of Theileria parva and control of East Coast fever—Current status and future trends
- Characterization of the Theileria parva sporozoite proteome
- Antibodies to in silico selected GPI-anchored Theileria parva proteins neutralize sporozoite infection in vitro
- BoLA-6*01301 and BoLA-6*01302, two allelic variants of the A18 haplotype, present the same epitope from the Tp1 antigen of Theileria parva
- Immune parameters to p67C antigen adjuvanted with ISA206VG correlate with protection against East Coast fever