Dissection of mechanisms of resistance to Aspergillus flavus and aflatoxin using tropical maize germplasm

Aspergillus flavus induced ear rots and subsequent contamination of maize (Zea mays L.) by aflatoxin is a serious food safety issue, especially in developing countries where the crop is mostly cultivated by smallholder famers for own consumption and income generation. A better understanding of the m...

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Main Authors: Garrido-Bazan, V., Mahuku, George S., Bibbins-Martinez, M., Arroyo-Bacerra, A., Villalobos-López, M.A.
Format: Journal Article
Language:Inglés
Published: Brill 2018
Subjects:
Online Access:https://hdl.handle.net/10568/92550
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author Garrido-Bazan, V.
Mahuku, George S.
Bibbins-Martinez, M.
Arroyo-Bacerra, A.
Villalobos-López, M.A.
author_browse Arroyo-Bacerra, A.
Bibbins-Martinez, M.
Garrido-Bazan, V.
Mahuku, George S.
Villalobos-López, M.A.
author_facet Garrido-Bazan, V.
Mahuku, George S.
Bibbins-Martinez, M.
Arroyo-Bacerra, A.
Villalobos-López, M.A.
author_sort Garrido-Bazan, V.
collection Repository of Agricultural Research Outputs (CGSpace)
description Aspergillus flavus induced ear rots and subsequent contamination of maize (Zea mays L.) by aflatoxin is a serious food safety issue, especially in developing countries where the crop is mostly cultivated by smallholder famers for own consumption and income generation. A better understanding of the mechanisms of resistance could help breeders to develop resistant maize varieties. In this study, a set of six tropical maize inbred lines previously identified as resistant or susceptible under natural field conditions were evaluated for response to A. flavus colonisation and aflatoxin contamination. Fungal biomass was significantly higher (P<0.05) in susceptible than resistant maize inbred lines, and this was highly correlated (P=0.001) to aflatoxin levels. Maize inbred lines MRI, MR2 and MR3 had low fungal biomass and low aflatoxin levels, suggesting that resistance in these lines was mediated through restricted fungal colonisation and establishment. Among the three putatively resistant inbred lines mentioned above, MR2 had a relatively high colonisation compared to the other two lines, revealing that A. flavus could establish and colonise kernels that were injured during inoculation, but did not contain high levels of aflatoxin. This could signify the presence of host genes that interfere with the aflatoxin biosynthetic pathway.
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spelling CGSpace925502025-01-27T15:00:52Z Dissection of mechanisms of resistance to Aspergillus flavus and aflatoxin using tropical maize germplasm Garrido-Bazan, V. Mahuku, George S. Bibbins-Martinez, M. Arroyo-Bacerra, A. Villalobos-López, M.A. maize aspergillus flavus aflatoxins resistance food security Aspergillus flavus induced ear rots and subsequent contamination of maize (Zea mays L.) by aflatoxin is a serious food safety issue, especially in developing countries where the crop is mostly cultivated by smallholder famers for own consumption and income generation. A better understanding of the mechanisms of resistance could help breeders to develop resistant maize varieties. In this study, a set of six tropical maize inbred lines previously identified as resistant or susceptible under natural field conditions were evaluated for response to A. flavus colonisation and aflatoxin contamination. Fungal biomass was significantly higher (P<0.05) in susceptible than resistant maize inbred lines, and this was highly correlated (P=0.001) to aflatoxin levels. Maize inbred lines MRI, MR2 and MR3 had low fungal biomass and low aflatoxin levels, suggesting that resistance in these lines was mediated through restricted fungal colonisation and establishment. Among the three putatively resistant inbred lines mentioned above, MR2 had a relatively high colonisation compared to the other two lines, revealing that A. flavus could establish and colonise kernels that were injured during inoculation, but did not contain high levels of aflatoxin. This could signify the presence of host genes that interfere with the aflatoxin biosynthetic pathway. 2018-04-25 2018-05-15T09:42:29Z 2018-05-15T09:42:29Z Journal Article https://hdl.handle.net/10568/92550 en Limited Access Brill Garrido-Bazan, V., Mahuku, G., Bibbins-Martinez, M., Arroyo-Bacerra, A. & Villalobos-López, M.Á. (2018). Dissection of mechanisms of resistance to Aspergillus flavus and aflatoxin using tropical maize germplasm. World Mycotoxin Journal, 11(2), 215-224.
spellingShingle maize
aspergillus flavus
aflatoxins
resistance
food security
Garrido-Bazan, V.
Mahuku, George S.
Bibbins-Martinez, M.
Arroyo-Bacerra, A.
Villalobos-López, M.A.
Dissection of mechanisms of resistance to Aspergillus flavus and aflatoxin using tropical maize germplasm
title Dissection of mechanisms of resistance to Aspergillus flavus and aflatoxin using tropical maize germplasm
title_full Dissection of mechanisms of resistance to Aspergillus flavus and aflatoxin using tropical maize germplasm
title_fullStr Dissection of mechanisms of resistance to Aspergillus flavus and aflatoxin using tropical maize germplasm
title_full_unstemmed Dissection of mechanisms of resistance to Aspergillus flavus and aflatoxin using tropical maize germplasm
title_short Dissection of mechanisms of resistance to Aspergillus flavus and aflatoxin using tropical maize germplasm
title_sort dissection of mechanisms of resistance to aspergillus flavus and aflatoxin using tropical maize germplasm
topic maize
aspergillus flavus
aflatoxins
resistance
food security
url https://hdl.handle.net/10568/92550
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