Evidence for negative selection of gene variants that increase dependence on dietary choline in a Gambian cohort

Choline is an essential nutrient, and the amount needed in the diet is modulated by several factors. Given geographical differences in dietary choline intake and disparate frequencies of single-nucleotide polymorphisms (SNPs) in choline metabolism genes between ethnic groups, we tested the hypothesi...

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Bibliographic Details
Main Authors: Silver, M.J., Corbin, K.D., Hellenthal, G., Costa, K.A. da, Domínguez Salas, Paula, Moore, S.E., Owen, J., Prentice, A.M., Hennig, B.J., Zeisel, S.H.
Format: Journal Article
Language:Inglés
Published: Wiley 2015
Online Access:https://hdl.handle.net/10568/68515

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