Maternal nutrition at conception modulates DNA methylation of human metastable epialleles
In experimental animals, maternal diet during the periconceptional period influences the establishment of DNA methylation at metastable epialleles in the offspring, with permanent phenotypic consequences. Pronounced naturally occurring seasonal differences in the diet of rural Gambian women allowed...
| Autores principales: | , , , , , , , , , , , , , , , |
|---|---|
| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
Springer
2014
|
| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/52239 |
Ejemplares similares: Maternal nutrition at conception modulates DNA methylation of human metastable epialleles
- Interindividual variation in DNA methylation at a putative POMC metastable epiallele is associated with obesity
- Independent genomewide screens identify the tumor suppressor VTRNA2-1 as a human epiallele responsive to periconceptional environment
- Exposure to aflatoxin B1 in utero is associated with DNA methylation in white blood cells of infants in The Gambia
- Evidence for negative selection of gene variants that increase dependence on dietary choline in a Gambian cohort
- Natural occurring epialleles determine vitamin E accumulation in tomato fruits
- Seasonal and gestation-stage associated differences in aflatoxin exposure in pregnant Gambian women