Exploiting host immunity and parasite genomics to develop a robust sub-unit vaccine against East Coast fever in cattle - Where are we?

Theileria parva, a tick-borne api-complexan protozoan parasite, causes East Coast fever (ECF) in cattle. Control of the disease by improved vaccination is believed to provide a sustainable solution. Class I MHC-restricted CD8+ cytotoxic T lymphocytes (CTL) directed at schizontinfected cells constitu...

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Bibliographic Details

Main Authors:	Mwangi, David Miano, Graham, S.P., Pelle, Roger, Honda, Y., Tonukari, N.J., Yamage, I.M., Glew, E.J., Villiers, Etienne P. de, Shah, Tushaar, Bishop, Richard P., Abuya, E., Awino, Elias, Gachanja, J., Luyai, A.E., Mbwika, F., Muthiani, A.M., Ndegwa, D.M., Njahira, Moses N., Nyanjui, J.K., Onono, F.O., Osaso, J., Saya, Rosemary M., Wildmann, C., Fraser, C.M., Maudlin, I., Gardner, M.J., Morzaria, S.P., Loosmore, S., Gilbert, S.C., Audonnet, J.C., Bruggen, P. van der, Nene, Vishvanath M., Taracha, E.L.N.
Format:	Conference Paper
Language:	Inglés
Published:	Tanzania Society for Animal Production 2006
Subjects:	cattle east coast fever genomes immunity disease resistance hosts theileria parva vaccines parasites antigens technology immunogenetics
Online Access:	https://hdl.handle.net/10568/50513