Characterization of the novel Trypanosoma brucei inosine 5′-monophosphate dehydrogenase
There is an alarming rate of human African trypanosomiasis recrudescence in many parts of sub-Saharan Africa. Yet, the disease has no successful chemotherapy. Trypanosoma lacks the enzymatic machinery for the de novo synthesis of purine nucleotides, and is critically dependent on salvage mechanisms....
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
Cambridge University Press
2013
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/41905 |
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