In vivo inhibition of trypanosome mitochondrial topoisomerase II: Effects of kinetoplast DNA maxicircles
Kinetoplast DNA, the mitochondrial DNA of trypanosomes, is a topologically complex structure composed of interlocked minicircles and maxicircles. We previously reported that etoposide, a potent inhibitor of topoisomerase II, promotes the cleavage of about 20% of network minicircle DNA (T. A. Shapiro...
| Main Authors: | , |
|---|---|
| Format: | Journal Article |
| Language: | Inglés |
| Published: |
Informa UK Limited
1994
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/33069 |
Similar Items: In vivo inhibition of trypanosome mitochondrial topoisomerase II: Effects of kinetoplast DNA maxicircles
- Maxicircle DNA and edited mRNA sequences of closely related trypanosome species: Implications of kRNA editing for evolution at maxicircle
- Modulation of mitochondrial electrical potential: A candidate mechanism for drug resistance in African trypanosomes
- Telomeric features of Theileria parva mitochondrial DNA derived from cycle sequence data of total genomic DNA
- PCR analysis of mitochondrial DNA polymorphism in N'Dama and Zebu cattle
- Inhibition of topoisomerases in African trypanosomes
- Analysis of mitochondrial D-loop region casts new light on domestic water buffalo (Bubalus bubalis) phylogeny