Pyroglutamyl peptidase type I from Trypanosoma brucei: A new virulence factor from African trypanosomes that de-blocks regulatory peptides in the plasma of infected hosts

Peptidases of parasitic protozoans are emerging as novel virulence factors and therapeutic targets in parasitic infections. A trypanosome-derived aminopeptidase that exclusively hydrolysed substrates with Glp (pyroglutamic acid) in P1 was purified 9248-fold from the plasma of rats infected with Tryp...

Full description

Bibliographic Details
Main Authors: Morty, R.E., Bulau, P., Pelle, Roger, Wilki, S., Abe, K.
Format: Journal Article
Language:Inglés
Published: Portland Press Ltd. 2006
Subjects:
Online Access:https://hdl.handle.net/10568/30093

Similar Items: Pyroglutamyl peptidase type I from Trypanosoma brucei: A new virulence factor from African trypanosomes that de-blocks regulatory peptides in the plasma of infected hosts