Gene-modified genotype II live attenuated African swine fever virus induces cross-protection against genotype I but not against genotype IX
African swine fever virus originated in a wildlife cycle in East Africa and spread to domestic pigs. At least twenty-three genotypes are present in Africa whereas only genotypes I and II have spread to other continents. Vaccine development has been directed mainly to genotype II. The ability of geno...
| Main Authors: | , , , , |
|---|---|
| Format: | Journal Article |
| Language: | Inglés |
| Published: |
Informa UK Limited
2025
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/174531 |
Similar Items: Gene-modified genotype II live attenuated African swine fever virus induces cross-protection against genotype I but not against genotype IX
- Co-deletion of A238L and EP402R genes from a genotype IX African swine fever virus results in partial attenuation and protection in swine
- Complete genome sequencing and comparative phylogenomics of nine African swine fever virus (ASFV) isolates of the virulent East African p72 genotype IX without viral sequence enrichment
- Rapid CRISPR/Cas9 editing of genotype IX African swine fever virus circulating in eastern and central Africa
- A rosin-functionalized plastic surface inactivates African swine fever virus
- The African swine fever isolate ASFV-Kenya-IX-1033 is highly virulent and stable after propagation in the wild boar cell line WSL
- Accelerated development of genotype IX African swine fever virus vaccine candidates using rapid CRISPR/Cas9 editing