Carotenoid composition and sequestration in cassava (Manihot esculentum Crantz) roots

Cassava ( Manihot esculentum Crantz ) is a staple food source for many developing countries. Its edible roots are high in starch but lack micronutrients such as β-carotene. In the present study, analysis of pedigree breeding populations has led to the identification of cassava accessions with enhanc...

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Autores principales: Drapal, Margit, Ovalle Rivera, Tatiana Melissa, Becerra Lopez Lavalle, Luis Augusto, Fraser, Paul D.
Formato: Journal Article
Lenguaje:Inglés
Publicado: 2024
Materias:
Acceso en línea:https://hdl.handle.net/10568/173756
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author Drapal, Margit
Ovalle Rivera, Tatiana Melissa
Becerra Lopez Lavalle, Luis Augusto
Fraser, Paul D.
author_browse Becerra Lopez Lavalle, Luis Augusto
Drapal, Margit
Fraser, Paul D.
Ovalle Rivera, Tatiana Melissa
author_facet Drapal, Margit
Ovalle Rivera, Tatiana Melissa
Becerra Lopez Lavalle, Luis Augusto
Fraser, Paul D.
author_sort Drapal, Margit
collection Repository of Agricultural Research Outputs (CGSpace)
description Cassava ( Manihot esculentum Crantz ) is a staple food source for many developing countries. Its edible roots are high in starch but lack micronutrients such as β-carotene. In the present study, analysis of pedigree breeding populations has led to the identification of cassava accessions with enhanced β-carotene contents up to 40 μg/g DW. This represents 0.2% of the Recommended Daily Allowance (RDA) for vitamin A. The β-branch of the carotenoid pathway predominates in cassava roots, with dominant levels of β-carotene followed by other minor epoxides of β-ring derived carotenoids. Metabolomic analysis revealed that steady state levels of intermediary metabolism were not altered by the formation of carotenoids, similar to starch and carbohydrate levels. Apocarotenoids appeared to be independent of their carotenoid precursors. Lipidomic analysis provided evidence of a significant positive correlation between carotenoid and lipid content, in particular plastid specific galactolipids. Proteomic analysis of isolated amyloplasts identified the majority of proteins associated with translation and carbohydrate/starch biosynthesis (e.g. glucose-1-phosphate adenylyltransferase). No carotenoid related proteins were detected even in the highest carotenoid containing lines. Carotenoids were associated with fractions typically annotated as plastoglobuli and plastid membranes (particularly the envelope). Proteomic analysis confirmed these structures apart from plastoglobuli, thus potentially amyloplast structures may not contain classical plastoglobuli structures.
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spelling CGSpace1737562025-11-11T17:40:18Z Carotenoid composition and sequestration in cassava (Manihot esculentum Crantz) roots Drapal, Margit Ovalle Rivera, Tatiana Melissa Becerra Lopez Lavalle, Luis Augusto Fraser, Paul D. cassava plant breeding roots nutritive value carotenoids amyloplast Cassava ( Manihot esculentum Crantz ) is a staple food source for many developing countries. Its edible roots are high in starch but lack micronutrients such as β-carotene. In the present study, analysis of pedigree breeding populations has led to the identification of cassava accessions with enhanced β-carotene contents up to 40 μg/g DW. This represents 0.2% of the Recommended Daily Allowance (RDA) for vitamin A. The β-branch of the carotenoid pathway predominates in cassava roots, with dominant levels of β-carotene followed by other minor epoxides of β-ring derived carotenoids. Metabolomic analysis revealed that steady state levels of intermediary metabolism were not altered by the formation of carotenoids, similar to starch and carbohydrate levels. Apocarotenoids appeared to be independent of their carotenoid precursors. Lipidomic analysis provided evidence of a significant positive correlation between carotenoid and lipid content, in particular plastid specific galactolipids. Proteomic analysis of isolated amyloplasts identified the majority of proteins associated with translation and carbohydrate/starch biosynthesis (e.g. glucose-1-phosphate adenylyltransferase). No carotenoid related proteins were detected even in the highest carotenoid containing lines. Carotenoids were associated with fractions typically annotated as plastoglobuli and plastid membranes (particularly the envelope). Proteomic analysis confirmed these structures apart from plastoglobuli, thus potentially amyloplast structures may not contain classical plastoglobuli structures. 2024-11-18 2025-03-20T13:52:50Z 2025-03-20T13:52:50Z Journal Article https://hdl.handle.net/10568/173756 en Open Access application/pdf Drapal, M.; Ovalle Rivera, T.M.; Becerra Lopez Lavalle, L.A.; Fraser, P.D. (2024) Carotenoid composition and sequestration in cassava (Manihot esculentum Crantz) roots. PLoS ONE 19(11): e0312517. ISSN: 1932-6203
spellingShingle cassava
plant breeding
roots
nutritive value
carotenoids
amyloplast
Drapal, Margit
Ovalle Rivera, Tatiana Melissa
Becerra Lopez Lavalle, Luis Augusto
Fraser, Paul D.
Carotenoid composition and sequestration in cassava (Manihot esculentum Crantz) roots
title Carotenoid composition and sequestration in cassava (Manihot esculentum Crantz) roots
title_full Carotenoid composition and sequestration in cassava (Manihot esculentum Crantz) roots
title_fullStr Carotenoid composition and sequestration in cassava (Manihot esculentum Crantz) roots
title_full_unstemmed Carotenoid composition and sequestration in cassava (Manihot esculentum Crantz) roots
title_short Carotenoid composition and sequestration in cassava (Manihot esculentum Crantz) roots
title_sort carotenoid composition and sequestration in cassava manihot esculentum crantz roots
topic cassava
plant breeding
roots
nutritive value
carotenoids
amyloplast
url https://hdl.handle.net/10568/173756
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