In vitro models as tools for screening the relative bioavailabilities of provitamin A carotenoids in foods
This review is organized as follows. First, the characteristics of the digestion and absorption and the metabolism of vitamin A and carotenoids are briefly discussed in Sections 2 and 3, respectively. The numerous factors that affect carotenoid bioavailability are considered in Section 4. Section 5...
| Main Authors: | , |
|---|---|
| Format: | Libro |
| Language: | Inglés |
| Published: |
International Food Policy Research Institute
2005
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/159709 |
| _version_ | 1855529138750750720 |
|---|---|
| author | Failla, Mark L. Chitchumroonchokchai, Chureeporn |
| author_browse | Chitchumroonchokchai, Chureeporn Failla, Mark L. |
| author_facet | Failla, Mark L. Chitchumroonchokchai, Chureeporn |
| author_sort | Failla, Mark L. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | This review is organized as follows. First, the characteristics of the digestion and absorption and the metabolism of vitamin A and carotenoids are briefly discussed in Sections 2 and 3, respectively. The numerous factors that affect carotenoid bioavailability are considered in Section 4. Section 5 first presents an overview of the techniques used to determine the relative bioavailabilities of carotenoids in vivo, and then describes the biochemical and cellular methods that are used to investigate the gastrointestinal processes associated with the accessibility and cellular transport of carotenoids. Key results from studies employing in vitro methods are systematically reviewed in Section 6. Finally Section 7 directly compares the findings of in vivo and in vitro studies and, on the basis of this comparison, proposes the use of simulated digestion and Caco-2 cells as tools for the initial screening for the relative bioavailability of provitamin A carotenoids from staple foods prepared according to local methods. |
| format | Libro |
| id | CGSpace159709 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2005 |
| publishDateRange | 2005 |
| publishDateSort | 2005 |
| publisher | International Food Policy Research Institute |
| publisherStr | International Food Policy Research Institute |
| record_format | dspace |
| spelling | CGSpace1597092025-12-08T10:06:44Z In vitro models as tools for screening the relative bioavailabilities of provitamin A carotenoids in foods Failla, Mark L. Chitchumroonchokchai, Chureeporn retinol bioavailability trace elements digestion provitamins carotenoids This review is organized as follows. First, the characteristics of the digestion and absorption and the metabolism of vitamin A and carotenoids are briefly discussed in Sections 2 and 3, respectively. The numerous factors that affect carotenoid bioavailability are considered in Section 4. Section 5 first presents an overview of the techniques used to determine the relative bioavailabilities of carotenoids in vivo, and then describes the biochemical and cellular methods that are used to investigate the gastrointestinal processes associated with the accessibility and cellular transport of carotenoids. Key results from studies employing in vitro methods are systematically reviewed in Section 6. Finally Section 7 directly compares the findings of in vivo and in vitro studies and, on the basis of this comparison, proposes the use of simulated digestion and Caco-2 cells as tools for the initial screening for the relative bioavailability of provitamin A carotenoids from staple foods prepared according to local methods. 2005 2024-11-13T22:02:51Z 2024-11-13T22:02:51Z Book https://hdl.handle.net/10568/159709 en Open Access application/pdf International Food Policy Research Institute International Center for Tropical Agriculture Failla, Mark L.; and Chitchumroonchokchai, Chureeporn. 2005. In vitro models as tools for screening the relative bioavailabilities of provitamin A carotenoids in foods. HarvestPlus Technical Monograph Series 3. Washington, DC and Cali, Columbia: International Food Policy Research Institute and International Center for Tropical Agriculture. https://hdl.handle.net/10568/159709 |
| spellingShingle | retinol bioavailability trace elements digestion provitamins carotenoids Failla, Mark L. Chitchumroonchokchai, Chureeporn In vitro models as tools for screening the relative bioavailabilities of provitamin A carotenoids in foods |
| title | In vitro models as tools for screening the relative bioavailabilities of provitamin A carotenoids in foods |
| title_full | In vitro models as tools for screening the relative bioavailabilities of provitamin A carotenoids in foods |
| title_fullStr | In vitro models as tools for screening the relative bioavailabilities of provitamin A carotenoids in foods |
| title_full_unstemmed | In vitro models as tools for screening the relative bioavailabilities of provitamin A carotenoids in foods |
| title_short | In vitro models as tools for screening the relative bioavailabilities of provitamin A carotenoids in foods |
| title_sort | in vitro models as tools for screening the relative bioavailabilities of provitamin a carotenoids in foods |
| topic | retinol bioavailability trace elements digestion provitamins carotenoids |
| url | https://hdl.handle.net/10568/159709 |
| work_keys_str_mv | AT faillamarkl invitromodelsastoolsforscreeningtherelativebioavailabilitiesofprovitaminacarotenoidsinfoods AT chitchumroonchokchaichureeporn invitromodelsastoolsforscreeningtherelativebioavailabilitiesofprovitaminacarotenoidsinfoods |