An algorithm to assess calcium bioavailability from foods

Background The recommended calcium intakes to meet calcium requirements at various ages are based on average population absorption values. Absorption is altered by physiology, the calcium load, and type of food. The calcium intake necessary, therefore, to meet requirements depends upon diet composit...

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Autores principales: Weaver, Connie M., Wastney, Meryl, Fletcher, Andrew, Lividini, Keith
Formato: Journal Article
Lenguaje:Inglés
Publicado: Elsevier 2024
Materias:
Acceso en línea:https://hdl.handle.net/10568/139849
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author Weaver, Connie M.
Wastney, Meryl
Fletcher, Andrew
Lividini, Keith
author_browse Fletcher, Andrew
Lividini, Keith
Wastney, Meryl
Weaver, Connie M.
author_facet Weaver, Connie M.
Wastney, Meryl
Fletcher, Andrew
Lividini, Keith
author_sort Weaver, Connie M.
collection Repository of Agricultural Research Outputs (CGSpace)
description Background The recommended calcium intakes to meet calcium requirements at various ages are based on average population absorption values. Absorption is altered by physiology, the calcium load, and type of food. The calcium intake necessary, therefore, to meet requirements depends upon diet composition, through bioavailability. Objective The objectives of this study was to improve predictions of calcium bioavailability on the basis of the food matrix. Methods We modeled calcium absorption data from individual foods, beverages, and fortified foods that were determined with calcium isotopic tracers and compared with milk as a referent to adjust for physiologic differences of the host. Results Data from 496 observations were modeled to develop a predictive algorithm for calcium bioavailability in adults on the basis of calcium load and oxalate and phytate loads, which represent the 2 main inhibitors of calcium absorption. Conclusions This algorithm will be helpful in assessing calcium availability from the food supply, for developing diets for individuals and research cohorts, and for designing policies and interventions to address inadequate calcium intake for populations.
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spelling CGSpace1398492025-12-08T10:06:44Z An algorithm to assess calcium bioavailability from foods Weaver, Connie M. Wastney, Meryl Fletcher, Andrew Lividini, Keith calcium absorption food nutrients bioavailability modelling fortified foods Background The recommended calcium intakes to meet calcium requirements at various ages are based on average population absorption values. Absorption is altered by physiology, the calcium load, and type of food. The calcium intake necessary, therefore, to meet requirements depends upon diet composition, through bioavailability. Objective The objectives of this study was to improve predictions of calcium bioavailability on the basis of the food matrix. Methods We modeled calcium absorption data from individual foods, beverages, and fortified foods that were determined with calcium isotopic tracers and compared with milk as a referent to adjust for physiologic differences of the host. Results Data from 496 observations were modeled to develop a predictive algorithm for calcium bioavailability in adults on the basis of calcium load and oxalate and phytate loads, which represent the 2 main inhibitors of calcium absorption. Conclusions This algorithm will be helpful in assessing calcium availability from the food supply, for developing diets for individuals and research cohorts, and for designing policies and interventions to address inadequate calcium intake for populations. 2024-03 2024-03-06T21:14:24Z 2024-03-06T21:14:24Z Journal Article https://hdl.handle.net/10568/139849 en Open Access Elsevier Weaver, Connie M.; Wastney, Meryl; Fletcher, Andrew; and Lividini, Keith. 2024. An algorithm to assess calcium bioavailability from foods. Journal of Nutrition 154(3): 921-927. https://doi.org/10.1016/j.tjnut.2023.12.005
spellingShingle calcium
absorption
food
nutrients
bioavailability
modelling
fortified foods
Weaver, Connie M.
Wastney, Meryl
Fletcher, Andrew
Lividini, Keith
An algorithm to assess calcium bioavailability from foods
title An algorithm to assess calcium bioavailability from foods
title_full An algorithm to assess calcium bioavailability from foods
title_fullStr An algorithm to assess calcium bioavailability from foods
title_full_unstemmed An algorithm to assess calcium bioavailability from foods
title_short An algorithm to assess calcium bioavailability from foods
title_sort algorithm to assess calcium bioavailability from foods
topic calcium
absorption
food
nutrients
bioavailability
modelling
fortified foods
url https://hdl.handle.net/10568/139849
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