Escape from CD8+ T Cell Response by Natural Variants of an Immunodominant Epitope from Theileria parva Is Predominantly Due to Loss of TCR Recognition
Polymorphism of immunodominant CD8+ T cell epitopes can facilitate escape from immune recognition of pathogens, leading to strain-specific immunity. In this study, we examined the TCR β-chain (TRB) diversity of the CD8+ T cell responses of cattle against two immunodominant epitopes from Theileria pa...
| Main Authors: | , , , , |
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| Format: | Journal Article |
| Language: | Inglés |
| Published: |
American Association of Immunologists
2011
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/129357 |
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