Evaluation of Pneumococcal Load in Blood by Polymerase Chain Reaction for the Diagnosis of Pneumococcal Pneumonia in Young Children in the PERCH Study

Detection of pneumococcus by lytA polymerase chain reaction (PCR) in blood had poor diagnostic accuracy for diagnosing pneumococcal pneumonia in children in 9 African and Asian sites. We assessed the value of blood lytA quantification in diagnosing pneumococcal pneumonia. The Pneumonia Etiology Rese...

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Main Authors: Deloria Knoll, Maria, Morpeth, Susan C., Scott, J.Anthony G., Watson, Nora L., Park, Daniel E., Baggett, Henry C., Brooks, W. Abdullah, Feikin, Daniel R., Hammitt, Laura L., Howie, Stephen R.C., Kotloff, Karen L., Levine, Orin S., O’Brien, Katherine L., Thea, Donald M., Ahmed, Dilruba, Antonio, Martin, Awori, Juliet O., Baillie, Vicky L., Chipeta, James, Deluca, Andrea N., Dione, Michel M., Driscoll, Amanda J., Higdon, Melissa M., Jatapai, Anchalee, Karron, Ruth A., Mazumder, Razib, Moore, David P., Mwansa, James, Nyongesa, Sammy, Prosperi, Christine, Seidenberg, Phil, Siludjai, Duangkamon, Sow, Samba O., Tamboura, Boubou, Zeger, Scott L., Murdoch, David R., Madhi, Shabir A., Knoll, Maria Deloria, Fancourt, Nicholas, Fu, Wei, Kagucia, E.Wangeci, Li, Mengying, Wu, Zhenke, Crawley, Jane, Endtz, Hubert P., Zaman, Khalequ, Goswami, Doli, Hossain, Lokman, Jahan, Yasmin, Ashraf, Hasan, Ebruke, Bernard E., McLellan, Jessica, Machuka, Eunice M., Shamsul, Arifin, Zaman, Syed M.A., Mackenzie, Grant, Kamau, Alice, Kazungu, Sidi, Ominde, Micah Silaba, Tapia, Milagritos D., Sylla, Mamadou, Onwuchekwa, Uma, Kourouma, Nana, Touré, Aliou, Adrian, Peter V., Kuwanda, Locadiah, Mudau, Azwifarwi, Groome, Michelle J., Mahomed, Nasreen, Thamthitiwat, Somsak, Maloney, Susan A., Bunthi, Charatdao, Rhodes, Julia, Sawatwong, Pongpun, Akarasewi, Pasakorn, Mwananyanda, Lawrence, Wa Somwe, Somwe, Kwenda, Geoffrey, Anderson, Trevor P., Mitchell, Joanne
Format: Journal Article
Language:Inglés
Published: Oxford University Press 2017
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Online Access:https://hdl.handle.net/10568/129300

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