Diagnostic and diversity of a novel secovirid affecting cassava in the Americas

We have developed a protocol for the detection, and characterization of pathogens in cassava (Manihot esculenta Crantz, Fam. Euphorbiaceae) widely cultivated in the tropics of Africa, Asia and Latin America. These processes guarantee the extraction of nucleic acids of high quality and yield to ensur...

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Main Authors: Jiménez Polo, Jenyfer, Leiva Sandoval, Ana Maria, Fernandez Huaytalla, Elizabeth, Bartolini, Ida, Cuéllar, Wilmer Jose
Format: Ponencia
Language:Inglés
Published: 2022
Subjects:
Online Access:https://hdl.handle.net/10568/126599
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author Jiménez Polo, Jenyfer
Leiva Sandoval, Ana Maria
Fernandez Huaytalla, Elizabeth
Bartolini, Ida
Cuéllar, Wilmer Jose
author_browse Bartolini, Ida
Cuéllar, Wilmer Jose
Fernandez Huaytalla, Elizabeth
Jiménez Polo, Jenyfer
Leiva Sandoval, Ana Maria
author_facet Jiménez Polo, Jenyfer
Leiva Sandoval, Ana Maria
Fernandez Huaytalla, Elizabeth
Bartolini, Ida
Cuéllar, Wilmer Jose
author_sort Jiménez Polo, Jenyfer
collection Repository of Agricultural Research Outputs (CGSpace)
description We have developed a protocol for the detection, and characterization of pathogens in cassava (Manihot esculenta Crantz, Fam. Euphorbiaceae) widely cultivated in the tropics of Africa, Asia and Latin America. These processes guarantee the extraction of nucleic acids of high quality and yield to ensure their use in the detection of DNA and RNA viruses and the sequencing of viral genomes. An average of 2.11 μg of nucleic acids per mg of dry tissue can be obtained using silica gel as a desiccant avoiding the use of liquid nitrogen and phenol. Diverse families of viruses infect cassava, causing significant economic losses and affecting food security. In the Americas, Cassava torrado-like virus (CsTLV) belongs to the Family Secoviridae, Genus Torradovirus have been found in mixed virus infections in Colombia and Brazil, associated with severe disease symptoms in leaves and roots of cassava. In single infections CsTLV can induce leaf chlorotic spots symptoms. Using Oxford Nanopore Technology we complete the genome sequence of a field isolate of CsTLV, showing the characteristic genome arrangement of members of the genus Torradovirus. interestingly CsTLV encodes an atypical Maf / HAM1 domain that functions in eukaryotes to protect cells against mutagenesis only present in heterologous viruses of the Potyviridae family. Using this protocol, we analyzed field surveys in Colombia and a cassava country-wide collection from Peru, detecting the diverse isolates of CsTLV and the occurrence of the virus in the Americas.
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spelling CGSpace1265992025-01-28T07:08:05Z Diagnostic and diversity of a novel secovirid affecting cassava in the Americas Jiménez Polo, Jenyfer Leiva Sandoval, Ana Maria Fernandez Huaytalla, Elizabeth Bartolini, Ida Cuéllar, Wilmer Jose cassava viruses nucleic acids extraction surveys ácidos nucléicos virus extracción We have developed a protocol for the detection, and characterization of pathogens in cassava (Manihot esculenta Crantz, Fam. Euphorbiaceae) widely cultivated in the tropics of Africa, Asia and Latin America. These processes guarantee the extraction of nucleic acids of high quality and yield to ensure their use in the detection of DNA and RNA viruses and the sequencing of viral genomes. An average of 2.11 μg of nucleic acids per mg of dry tissue can be obtained using silica gel as a desiccant avoiding the use of liquid nitrogen and phenol. Diverse families of viruses infect cassava, causing significant economic losses and affecting food security. In the Americas, Cassava torrado-like virus (CsTLV) belongs to the Family Secoviridae, Genus Torradovirus have been found in mixed virus infections in Colombia and Brazil, associated with severe disease symptoms in leaves and roots of cassava. In single infections CsTLV can induce leaf chlorotic spots symptoms. Using Oxford Nanopore Technology we complete the genome sequence of a field isolate of CsTLV, showing the characteristic genome arrangement of members of the genus Torradovirus. interestingly CsTLV encodes an atypical Maf / HAM1 domain that functions in eukaryotes to protect cells against mutagenesis only present in heterologous viruses of the Potyviridae family. Using this protocol, we analyzed field surveys in Colombia and a cassava country-wide collection from Peru, detecting the diverse isolates of CsTLV and the occurrence of the virus in the Americas. 2022-08-09 2023-01-05T09:11:59Z 2023-01-05T09:11:59Z Presentation https://hdl.handle.net/10568/126599 en Limited Access Jimenez Polo, J.; Leiva Sandoval, A.M.; Fernandez Huaytalla, E.; Bartolini, I.; Cuellar, W.J. (2022) Diagnostic and diversity of a novel secovirid affecting cassava in the Americas. 13 slides
spellingShingle cassava
viruses
nucleic acids
extraction
surveys
ácidos nucléicos
virus
extracción
Jiménez Polo, Jenyfer
Leiva Sandoval, Ana Maria
Fernandez Huaytalla, Elizabeth
Bartolini, Ida
Cuéllar, Wilmer Jose
Diagnostic and diversity of a novel secovirid affecting cassava in the Americas
title Diagnostic and diversity of a novel secovirid affecting cassava in the Americas
title_full Diagnostic and diversity of a novel secovirid affecting cassava in the Americas
title_fullStr Diagnostic and diversity of a novel secovirid affecting cassava in the Americas
title_full_unstemmed Diagnostic and diversity of a novel secovirid affecting cassava in the Americas
title_short Diagnostic and diversity of a novel secovirid affecting cassava in the Americas
title_sort diagnostic and diversity of a novel secovirid affecting cassava in the americas
topic cassava
viruses
nucleic acids
extraction
surveys
ácidos nucléicos
virus
extracción
url https://hdl.handle.net/10568/126599
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