Pharmaceutical pollution of the world’s rivers
Environmental exposure to active pharmaceutical ingredients (APIs) can have negative effects on the health of ecosystems and humans. While numerous studies have monitored APIs in rivers, these employ different analytical methods, measure different APIs, and have ignored many of the countries of the...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Journal Article |
| Language: | Inglés |
| Published: |
National Academy of Sciences
2022
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/118261 |
| _version_ | 1855517407642124288 |
|---|---|
| author | Wilkinson, J. L. Boxall, A. B. A. Kolpin, D. W. Leung, K. M. Y. Lai, R. W. S. Galban-Malagon, C. Adell, A. D. Mondon, J. Metian, M. Marchant, R. A. Bouzas-Monroy, A. Cuní-Sanchez, A. Coors, A. Carriquiriborde, P. Rojo, M. Gordon, C. Cara, M. Moermond, M. Luarte, T. Petrosyan, V. Perikhanyan, Y. Mahon, C. S. McGurk, C. J. Hofmann, T. Kormoker, T. Iniguez, V. Guzmán Otazo, J. Tavares, J. L. Figueiredo, F.G. de Razzolini, M. T. P. Dougnon, V. Gbaguidi, G. Traoré, O. Blais, J. M. Kimpe, L. E. Wong, M. Wong, D. Ntchantcho, R. Pizarro, J. Ying, G.-G. Chen, C.-E. Paez, M. Martínez Lara, J. Otamonga, J.-P. Pote, J. Ifo, S.A. Wilson, P. Echeverria-Saenz, S. Udikovic-Kolic, N. Milakovic, M. Fatta-Kassinos, D. Ioannou-Ttofa, L. Belusova, V. Vymazal, J. Cardenas-Bustamante, M. Kassa, B. A. Garric, J. Chaumot, A. Gibba, P. Kunchulia, I. Seidensticker, S. Lyberatos, G. Halldorsson, H. P. Melling, M. Shashidhar, T. Lamba, M. Nastiti, A. Supriatin, A. Pourang, N. Abedini, A. Abdullah, O. Gharbia, S. S. Pilla, F. Chefetz, B. Topaz, T. Yao, K. M. Aubakirova, B. Beisenova, R. Olaka, L. Mulu, J. K. Chatanga, P. Ntuli, V. Blama, N. T. Sherif, S. Aris, A. Z. Looi, L. J. Niang, M. Traoré, S.T. Oldenkamp, R. Ogunbanwo, O. Ashfaq, M. Iqbal, M. Abdeen, Z. O’Dea, A. Morales Saldana, J. M. Custodio, M. Cruz, H. de la Navarrete, I. Carvalho, F. Gogra, A. B. Koroma, B. M. Cerkvenik-Flajs, V. Gombac, M. Thwala, M. Choi, K. Kang, H. Ladu, J. L. C. Rico, A. Amerasinghe, Priyanie Sobek, A. Horlitz, G. Zenker, A. K. King, A.C. Jiang, J.-J. Kariuki, R. Tumbo, M. Tezel, U. Onay, T. T. Lejju, J. B. Vystavna, Y. Vergeles, Y. Heinzen, H. Perez-Parada, A. Sims, D. B. Figy, M. Good, D. Teta, C. |
| author_browse | Abdeen, Z. Abdullah, O. Abedini, A. Adell, A. D. Amerasinghe, Priyanie Aris, A. Z. Ashfaq, M. Aubakirova, B. Beisenova, R. Belusova, V. Blais, J. M. Blama, N. T. Bouzas-Monroy, A. Boxall, A. B. A. Cara, M. Cardenas-Bustamante, M. Carriquiriborde, P. Carvalho, F. Cerkvenik-Flajs, V. Chatanga, P. Chaumot, A. Chefetz, B. Chen, C.-E. Choi, K. Coors, A. Cruz, H. de la Cuní-Sanchez, A. Custodio, M. Dougnon, V. Echeverria-Saenz, S. Fatta-Kassinos, D. Figueiredo, F.G. de Figy, M. Galban-Malagon, C. Garric, J. Gbaguidi, G. Gharbia, S. S. Gibba, P. Gogra, A. B. Gombac, M. Good, D. Gordon, C. Guzmán Otazo, J. Halldorsson, H. P. Heinzen, H. Hofmann, T. Horlitz, G. Ifo, S.A. Iniguez, V. Ioannou-Ttofa, L. Iqbal, M. Jiang, J.-J. Kang, H. Kariuki, R. Kassa, B. A. Kimpe, L. E. King, A.C. Kolpin, D. W. Kormoker, T. Koroma, B. M. Kunchulia, I. Ladu, J. L. C. Lai, R. W. S. Lamba, M. Lejju, J. B. Leung, K. M. Y. Looi, L. J. Luarte, T. Lyberatos, G. Mahon, C. S. Marchant, R. A. Martínez Lara, J. McGurk, C. J. Melling, M. Metian, M. Milakovic, M. Moermond, M. Mondon, J. Morales Saldana, J. M. Mulu, J. K. Nastiti, A. Navarrete, I. Niang, M. Ntchantcho, R. Ntuli, V. Ogunbanwo, O. Olaka, L. Oldenkamp, R. Onay, T. T. Otamonga, J.-P. O’Dea, A. Paez, M. Perez-Parada, A. Perikhanyan, Y. Petrosyan, V. Pilla, F. Pizarro, J. Pote, J. Pourang, N. Razzolini, M. T. P. Rico, A. Rojo, M. Seidensticker, S. Shashidhar, T. Sherif, S. Sims, D. B. Sobek, A. Supriatin, A. Tavares, J. L. Teta, C. Tezel, U. Thwala, M. Topaz, T. Traoré, O. Traoré, S.T. Tumbo, M. Udikovic-Kolic, N. Vergeles, Y. Vymazal, J. Vystavna, Y. Wilkinson, J. L. Wilson, P. Wong, D. Wong, M. Yao, K. M. Ying, G.-G. Zenker, A. K. |
| author_facet | Wilkinson, J. L. Boxall, A. B. A. Kolpin, D. W. Leung, K. M. Y. Lai, R. W. S. Galban-Malagon, C. Adell, A. D. Mondon, J. Metian, M. Marchant, R. A. Bouzas-Monroy, A. Cuní-Sanchez, A. Coors, A. Carriquiriborde, P. Rojo, M. Gordon, C. Cara, M. Moermond, M. Luarte, T. Petrosyan, V. Perikhanyan, Y. Mahon, C. S. McGurk, C. J. Hofmann, T. Kormoker, T. Iniguez, V. Guzmán Otazo, J. Tavares, J. L. Figueiredo, F.G. de Razzolini, M. T. P. Dougnon, V. Gbaguidi, G. Traoré, O. Blais, J. M. Kimpe, L. E. Wong, M. Wong, D. Ntchantcho, R. Pizarro, J. Ying, G.-G. Chen, C.-E. Paez, M. Martínez Lara, J. Otamonga, J.-P. Pote, J. Ifo, S.A. Wilson, P. Echeverria-Saenz, S. Udikovic-Kolic, N. Milakovic, M. Fatta-Kassinos, D. Ioannou-Ttofa, L. Belusova, V. Vymazal, J. Cardenas-Bustamante, M. Kassa, B. A. Garric, J. Chaumot, A. Gibba, P. Kunchulia, I. Seidensticker, S. Lyberatos, G. Halldorsson, H. P. Melling, M. Shashidhar, T. Lamba, M. Nastiti, A. Supriatin, A. Pourang, N. Abedini, A. Abdullah, O. Gharbia, S. S. Pilla, F. Chefetz, B. Topaz, T. Yao, K. M. Aubakirova, B. Beisenova, R. Olaka, L. Mulu, J. K. Chatanga, P. Ntuli, V. Blama, N. T. Sherif, S. Aris, A. Z. Looi, L. J. Niang, M. Traoré, S.T. Oldenkamp, R. Ogunbanwo, O. Ashfaq, M. Iqbal, M. Abdeen, Z. O’Dea, A. Morales Saldana, J. M. Custodio, M. Cruz, H. de la Navarrete, I. Carvalho, F. Gogra, A. B. Koroma, B. M. Cerkvenik-Flajs, V. Gombac, M. Thwala, M. Choi, K. Kang, H. Ladu, J. L. C. Rico, A. Amerasinghe, Priyanie Sobek, A. Horlitz, G. Zenker, A. K. King, A.C. Jiang, J.-J. Kariuki, R. Tumbo, M. Tezel, U. Onay, T. T. Lejju, J. B. Vystavna, Y. Vergeles, Y. Heinzen, H. Perez-Parada, A. Sims, D. B. Figy, M. Good, D. Teta, C. |
| author_sort | Wilkinson, J. L. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Environmental exposure to active pharmaceutical ingredients (APIs) can have negative effects on the health of ecosystems and humans. While numerous studies have monitored APIs in rivers, these employ different analytical methods, measure different APIs, and have ignored many of the countries of the world. This makes it difficult to quantify the scale of the problem from a global perspective. Furthermore, comparison of the existing data, generated for different studies/regions/continents, is challenging due to the vast differences between the analytical methodologies employed. Here, we present a global-scale study of API pollution in 258 of the world’s rivers, representing the environmental influence of 471.4 million people across 137 geographic regions. Samples were obtained from 1,052 locations in 104 countries (representing all continents and 36 countries not previously studied for API contamination) and analyzed for 61 APIs. Highest cumulative API concentrations were observed in sub-Saharan Africa, south Asia, and South America. The most contaminated sites were in low- to middle-income countries and were associated with areas with poor wastewater and waste management infrastructure and pharmaceutical manufacturing. The most frequently detected APIs were carbamazepine, metformin, and caffeine (a compound also arising from lifestyle use), which were detected at over half of the sites monitored. Concentrations of at least one API at 25.7% of the sampling sites were greater than concentrations considered safe for aquatic organisms, or which are of concern in terms of selection for antimicrobial resistance. Therefore, pharmaceutical pollution poses a global threat to environmental and human health, as well as to delivery of the United Nations Sustainable Development Goals. |
| format | Journal Article |
| id | CGSpace118261 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2022 |
| publishDateRange | 2022 |
| publishDateSort | 2022 |
| publisher | National Academy of Sciences |
| publisherStr | National Academy of Sciences |
| record_format | dspace |
| spelling | CGSpace1182612025-10-26T12:53:20Z Pharmaceutical pollution of the world’s rivers Wilkinson, J. L. Boxall, A. B. A. Kolpin, D. W. Leung, K. M. Y. Lai, R. W. S. Galban-Malagon, C. Adell, A. D. Mondon, J. Metian, M. Marchant, R. A. Bouzas-Monroy, A. Cuní-Sanchez, A. Coors, A. Carriquiriborde, P. Rojo, M. Gordon, C. Cara, M. Moermond, M. Luarte, T. Petrosyan, V. Perikhanyan, Y. Mahon, C. S. McGurk, C. J. Hofmann, T. Kormoker, T. Iniguez, V. Guzmán Otazo, J. Tavares, J. L. Figueiredo, F.G. de Razzolini, M. T. P. Dougnon, V. Gbaguidi, G. Traoré, O. Blais, J. M. Kimpe, L. E. Wong, M. Wong, D. Ntchantcho, R. Pizarro, J. Ying, G.-G. Chen, C.-E. Paez, M. Martínez Lara, J. Otamonga, J.-P. Pote, J. Ifo, S.A. Wilson, P. Echeverria-Saenz, S. Udikovic-Kolic, N. Milakovic, M. Fatta-Kassinos, D. Ioannou-Ttofa, L. Belusova, V. Vymazal, J. Cardenas-Bustamante, M. Kassa, B. A. Garric, J. Chaumot, A. Gibba, P. Kunchulia, I. Seidensticker, S. Lyberatos, G. Halldorsson, H. P. Melling, M. Shashidhar, T. Lamba, M. Nastiti, A. Supriatin, A. Pourang, N. Abedini, A. Abdullah, O. Gharbia, S. S. Pilla, F. Chefetz, B. Topaz, T. Yao, K. M. Aubakirova, B. Beisenova, R. Olaka, L. Mulu, J. K. Chatanga, P. Ntuli, V. Blama, N. T. Sherif, S. Aris, A. Z. Looi, L. J. Niang, M. Traoré, S.T. Oldenkamp, R. Ogunbanwo, O. Ashfaq, M. Iqbal, M. Abdeen, Z. O’Dea, A. Morales Saldana, J. M. Custodio, M. Cruz, H. de la Navarrete, I. Carvalho, F. Gogra, A. B. Koroma, B. M. Cerkvenik-Flajs, V. Gombac, M. Thwala, M. Choi, K. Kang, H. Ladu, J. L. C. Rico, A. Amerasinghe, Priyanie Sobek, A. Horlitz, G. Zenker, A. K. King, A.C. Jiang, J.-J. Kariuki, R. Tumbo, M. Tezel, U. Onay, T. T. Lejju, J. B. Vystavna, Y. Vergeles, Y. Heinzen, H. Perez-Parada, A. Sims, D. B. Figy, M. Good, D. Teta, C. pharmaceutical pollution rivers water pollution contamination aquatic environment antimicrobials environmental health human health environmental monitoring wastewater socioeconomic aspects national income datasets Environmental exposure to active pharmaceutical ingredients (APIs) can have negative effects on the health of ecosystems and humans. While numerous studies have monitored APIs in rivers, these employ different analytical methods, measure different APIs, and have ignored many of the countries of the world. This makes it difficult to quantify the scale of the problem from a global perspective. Furthermore, comparison of the existing data, generated for different studies/regions/continents, is challenging due to the vast differences between the analytical methodologies employed. Here, we present a global-scale study of API pollution in 258 of the world’s rivers, representing the environmental influence of 471.4 million people across 137 geographic regions. Samples were obtained from 1,052 locations in 104 countries (representing all continents and 36 countries not previously studied for API contamination) and analyzed for 61 APIs. Highest cumulative API concentrations were observed in sub-Saharan Africa, south Asia, and South America. The most contaminated sites were in low- to middle-income countries and were associated with areas with poor wastewater and waste management infrastructure and pharmaceutical manufacturing. The most frequently detected APIs were carbamazepine, metformin, and caffeine (a compound also arising from lifestyle use), which were detected at over half of the sites monitored. Concentrations of at least one API at 25.7% of the sampling sites were greater than concentrations considered safe for aquatic organisms, or which are of concern in terms of selection for antimicrobial resistance. Therefore, pharmaceutical pollution poses a global threat to environmental and human health, as well as to delivery of the United Nations Sustainable Development Goals. 2022-02-22 2022-02-28T13:10:23Z 2022-02-28T13:10:23Z Journal Article https://hdl.handle.net/10568/118261 en Open Access National Academy of Sciences Wilkinson, J. L.; Boxall, A. B. A.; Kolpin, D. W.; Leung, K. M. Y.; Lai, R. W. S.; Galban-Malagon, C.; Adell, A. D.; Mondon, J.; Metian, M.; Marchant, R. A.; Bouzas-Monroy, A.; Cuni-Sanchez, A.; Coors, A.; Carriquiriborde, P.; Rojo, M.; Gordon, C.; Cara, M.; Moermond, M.; Luarte, T.; Petrosyan, V.; Perikhanyan, Y.; Mahon, C. S.; McGurk, C. J.; Hofmann, T.; Kormoker, T.; Iniguez, V.; Guzman-Otazo, J.; Tavares, J. L.; De Figueiredo, F. G.; Razzolini, M. T. P.; Dougnon, V.; Gbaguidi, G.; Traore, O.; Blais, J. M.; Kimpe, L. E.; Wong, M.; Wong, D.; Ntchantcho, R.; Pizarro, J.; Ying, G.-G.; Chen, C.-E.; Paez, M.; Martinez-Lara, J.; Otamonga, J.-P.; Pote, J.; Ifo, S. A.; Wilson, P.; Echeverria-Saenz, S.; Udikovic-Kolic, N.; Milakovic, M.; Fatta-Kassinos, D.; Ioannou-Ttofa, L.; Belusova, V.; Vymazal, J.; Cardenas-Bustamante, M.; Kassa, B. A.; Garric, J.; Chaumot, A.; Gibba, P.; Kunchulia, I.; Seidensticker, S.; Lyberatos, G.; Halldorsson, H. P.; Melling, M.; Shashidhar, T.; Lamba, M.; Nastiti, A.; Supriatin, A.; Pourang, N.; Abedini, A.; Abdullah, O.; Gharbia, S. S.; Pilla, F.; Chefetz, B.; Topaz, T.; Yao, K. M.; Aubakirova, B.; Beisenova, R.; Olaka, L.; Mulu, J. K.; Chatanga, P.; Ntuli, V.; Blama, N. T.; Sherif, S.; Aris, A. Z.; Looi, L. J.; Niang, M.; Traore, S. T.; Oldenkamp, R.; Ogunbanwo, O.; Ashfaq, M.; Iqbal, M.; Abdeen, Z.; O’Dea, A.; Morales-Saldana, J. M.; Custodio, M.; de la Cruz, H.; Navarrete, I.; Carvalho, F.; Gogra, A. B.; Koroma, B. M.; Cerkvenik-Flajs, V.; Gombac, M.; Thwala, M.; Choi, K.; Kang, H.; Ladu, J. L. C.; Rico, A.; Amerasinghe, Priyanie; Sobek, A.; Horlitz, G.; Zenker, A. K.; King, A. C.; Jiang, J.-J.; Kariuki, R.; Tumbo, M.; Tezel, U.; Onay, T. T.; Lejju, J. B.; Vystavna, Y.; Vergeles, Y.; Heinzen, H.; Perez-Parada, A.; Sims, D. B.; Figy, M.; Good, D.; Teta, C. 2022. Pharmaceutical pollution of the world’s rivers. Proceedings of the National Academy of Sciences of the United States of America, 119(8):e2113947119. [doi: https://doi.org/10.1073/pnas.2113947119] |
| spellingShingle | pharmaceutical pollution rivers water pollution contamination aquatic environment antimicrobials environmental health human health environmental monitoring wastewater socioeconomic aspects national income datasets Wilkinson, J. L. Boxall, A. B. A. Kolpin, D. W. Leung, K. M. Y. Lai, R. W. S. Galban-Malagon, C. Adell, A. D. Mondon, J. Metian, M. Marchant, R. A. Bouzas-Monroy, A. Cuní-Sanchez, A. Coors, A. Carriquiriborde, P. Rojo, M. Gordon, C. Cara, M. Moermond, M. Luarte, T. Petrosyan, V. Perikhanyan, Y. Mahon, C. S. McGurk, C. J. Hofmann, T. Kormoker, T. Iniguez, V. Guzmán Otazo, J. Tavares, J. L. Figueiredo, F.G. de Razzolini, M. T. P. Dougnon, V. Gbaguidi, G. Traoré, O. Blais, J. M. Kimpe, L. E. Wong, M. Wong, D. Ntchantcho, R. Pizarro, J. Ying, G.-G. Chen, C.-E. Paez, M. Martínez Lara, J. Otamonga, J.-P. Pote, J. Ifo, S.A. Wilson, P. Echeverria-Saenz, S. Udikovic-Kolic, N. Milakovic, M. Fatta-Kassinos, D. Ioannou-Ttofa, L. Belusova, V. Vymazal, J. Cardenas-Bustamante, M. Kassa, B. A. Garric, J. Chaumot, A. Gibba, P. Kunchulia, I. Seidensticker, S. Lyberatos, G. Halldorsson, H. P. Melling, M. Shashidhar, T. Lamba, M. Nastiti, A. Supriatin, A. Pourang, N. Abedini, A. Abdullah, O. Gharbia, S. S. Pilla, F. Chefetz, B. Topaz, T. Yao, K. M. Aubakirova, B. Beisenova, R. Olaka, L. Mulu, J. K. Chatanga, P. Ntuli, V. Blama, N. T. Sherif, S. Aris, A. Z. Looi, L. J. Niang, M. Traoré, S.T. Oldenkamp, R. Ogunbanwo, O. Ashfaq, M. Iqbal, M. Abdeen, Z. O’Dea, A. Morales Saldana, J. M. Custodio, M. Cruz, H. de la Navarrete, I. Carvalho, F. Gogra, A. B. Koroma, B. M. Cerkvenik-Flajs, V. Gombac, M. Thwala, M. Choi, K. Kang, H. Ladu, J. L. C. Rico, A. Amerasinghe, Priyanie Sobek, A. Horlitz, G. Zenker, A. K. King, A.C. Jiang, J.-J. Kariuki, R. Tumbo, M. Tezel, U. Onay, T. T. Lejju, J. B. Vystavna, Y. Vergeles, Y. Heinzen, H. Perez-Parada, A. Sims, D. B. Figy, M. Good, D. Teta, C. Pharmaceutical pollution of the world’s rivers |
| title | Pharmaceutical pollution of the world’s rivers |
| title_full | Pharmaceutical pollution of the world’s rivers |
| title_fullStr | Pharmaceutical pollution of the world’s rivers |
| title_full_unstemmed | Pharmaceutical pollution of the world’s rivers |
| title_short | Pharmaceutical pollution of the world’s rivers |
| title_sort | pharmaceutical pollution of the world s rivers |
| topic | pharmaceutical pollution rivers water pollution contamination aquatic environment antimicrobials environmental health human health environmental monitoring wastewater socioeconomic aspects national income datasets |
| url | https://hdl.handle.net/10568/118261 |
| work_keys_str_mv | AT wilkinsonjl pharmaceuticalpollutionoftheworldsrivers AT boxallaba pharmaceuticalpollutionoftheworldsrivers AT kolpindw pharmaceuticalpollutionoftheworldsrivers AT leungkmy pharmaceuticalpollutionoftheworldsrivers AT lairws pharmaceuticalpollutionoftheworldsrivers AT galbanmalagonc pharmaceuticalpollutionoftheworldsrivers AT adellad pharmaceuticalpollutionoftheworldsrivers AT mondonj pharmaceuticalpollutionoftheworldsrivers AT metianm pharmaceuticalpollutionoftheworldsrivers AT marchantra pharmaceuticalpollutionoftheworldsrivers AT bouzasmonroya pharmaceuticalpollutionoftheworldsrivers AT cunisancheza pharmaceuticalpollutionoftheworldsrivers AT coorsa pharmaceuticalpollutionoftheworldsrivers AT carriquiribordep pharmaceuticalpollutionoftheworldsrivers AT rojom pharmaceuticalpollutionoftheworldsrivers AT gordonc pharmaceuticalpollutionoftheworldsrivers AT caram pharmaceuticalpollutionoftheworldsrivers AT moermondm pharmaceuticalpollutionoftheworldsrivers AT luartet pharmaceuticalpollutionoftheworldsrivers AT petrosyanv pharmaceuticalpollutionoftheworldsrivers AT perikhanyany pharmaceuticalpollutionoftheworldsrivers AT mahoncs pharmaceuticalpollutionoftheworldsrivers AT mcgurkcj pharmaceuticalpollutionoftheworldsrivers AT hofmannt pharmaceuticalpollutionoftheworldsrivers AT kormokert pharmaceuticalpollutionoftheworldsrivers AT iniguezv pharmaceuticalpollutionoftheworldsrivers AT guzmanotazoj pharmaceuticalpollutionoftheworldsrivers AT tavaresjl pharmaceuticalpollutionoftheworldsrivers AT figueiredofgde pharmaceuticalpollutionoftheworldsrivers AT razzolinimtp pharmaceuticalpollutionoftheworldsrivers AT dougnonv pharmaceuticalpollutionoftheworldsrivers AT gbaguidig pharmaceuticalpollutionoftheworldsrivers AT traoreo pharmaceuticalpollutionoftheworldsrivers AT blaisjm pharmaceuticalpollutionoftheworldsrivers AT kimpele pharmaceuticalpollutionoftheworldsrivers AT wongm pharmaceuticalpollutionoftheworldsrivers AT wongd pharmaceuticalpollutionoftheworldsrivers AT ntchantchor pharmaceuticalpollutionoftheworldsrivers AT pizarroj pharmaceuticalpollutionoftheworldsrivers AT yinggg pharmaceuticalpollutionoftheworldsrivers AT chence pharmaceuticalpollutionoftheworldsrivers AT paezm pharmaceuticalpollutionoftheworldsrivers AT martinezlaraj pharmaceuticalpollutionoftheworldsrivers AT otamongajp pharmaceuticalpollutionoftheworldsrivers AT potej pharmaceuticalpollutionoftheworldsrivers AT ifosa pharmaceuticalpollutionoftheworldsrivers AT wilsonp pharmaceuticalpollutionoftheworldsrivers AT echeverriasaenzs pharmaceuticalpollutionoftheworldsrivers AT udikovickolicn pharmaceuticalpollutionoftheworldsrivers AT milakovicm pharmaceuticalpollutionoftheworldsrivers AT fattakassinosd pharmaceuticalpollutionoftheworldsrivers AT ioannouttofal pharmaceuticalpollutionoftheworldsrivers AT belusovav pharmaceuticalpollutionoftheworldsrivers AT vymazalj pharmaceuticalpollutionoftheworldsrivers AT cardenasbustamantem pharmaceuticalpollutionoftheworldsrivers AT kassaba pharmaceuticalpollutionoftheworldsrivers AT garricj pharmaceuticalpollutionoftheworldsrivers AT chaumota pharmaceuticalpollutionoftheworldsrivers AT gibbap pharmaceuticalpollutionoftheworldsrivers AT kunchuliai pharmaceuticalpollutionoftheworldsrivers AT seidenstickers pharmaceuticalpollutionoftheworldsrivers AT lyberatosg pharmaceuticalpollutionoftheworldsrivers AT halldorssonhp pharmaceuticalpollutionoftheworldsrivers AT mellingm pharmaceuticalpollutionoftheworldsrivers AT shashidhart pharmaceuticalpollutionoftheworldsrivers AT lambam pharmaceuticalpollutionoftheworldsrivers AT nastitia pharmaceuticalpollutionoftheworldsrivers AT supriatina pharmaceuticalpollutionoftheworldsrivers AT pourangn pharmaceuticalpollutionoftheworldsrivers AT abedinia pharmaceuticalpollutionoftheworldsrivers AT abdullaho pharmaceuticalpollutionoftheworldsrivers AT gharbiass pharmaceuticalpollutionoftheworldsrivers AT pillaf pharmaceuticalpollutionoftheworldsrivers AT chefetzb pharmaceuticalpollutionoftheworldsrivers AT topazt pharmaceuticalpollutionoftheworldsrivers AT yaokm pharmaceuticalpollutionoftheworldsrivers AT aubakirovab pharmaceuticalpollutionoftheworldsrivers AT beisenovar pharmaceuticalpollutionoftheworldsrivers AT olakal pharmaceuticalpollutionoftheworldsrivers AT mulujk pharmaceuticalpollutionoftheworldsrivers AT chatangap pharmaceuticalpollutionoftheworldsrivers AT ntuliv pharmaceuticalpollutionoftheworldsrivers AT blamant pharmaceuticalpollutionoftheworldsrivers AT sherifs pharmaceuticalpollutionoftheworldsrivers AT arisaz pharmaceuticalpollutionoftheworldsrivers AT looilj pharmaceuticalpollutionoftheworldsrivers AT niangm pharmaceuticalpollutionoftheworldsrivers AT traorest pharmaceuticalpollutionoftheworldsrivers AT oldenkampr pharmaceuticalpollutionoftheworldsrivers AT ogunbanwoo pharmaceuticalpollutionoftheworldsrivers AT ashfaqm pharmaceuticalpollutionoftheworldsrivers AT iqbalm pharmaceuticalpollutionoftheworldsrivers AT abdeenz pharmaceuticalpollutionoftheworldsrivers AT odeaa pharmaceuticalpollutionoftheworldsrivers AT moralessaldanajm pharmaceuticalpollutionoftheworldsrivers AT custodiom pharmaceuticalpollutionoftheworldsrivers AT cruzhdela pharmaceuticalpollutionoftheworldsrivers AT navarretei pharmaceuticalpollutionoftheworldsrivers AT carvalhof pharmaceuticalpollutionoftheworldsrivers AT gograab pharmaceuticalpollutionoftheworldsrivers AT koromabm pharmaceuticalpollutionoftheworldsrivers AT cerkvenikflajsv pharmaceuticalpollutionoftheworldsrivers AT gombacm pharmaceuticalpollutionoftheworldsrivers AT thwalam pharmaceuticalpollutionoftheworldsrivers AT choik pharmaceuticalpollutionoftheworldsrivers AT kangh pharmaceuticalpollutionoftheworldsrivers AT ladujlc pharmaceuticalpollutionoftheworldsrivers AT ricoa pharmaceuticalpollutionoftheworldsrivers AT amerasinghepriyanie pharmaceuticalpollutionoftheworldsrivers AT sobeka pharmaceuticalpollutionoftheworldsrivers AT horlitzg pharmaceuticalpollutionoftheworldsrivers AT zenkerak pharmaceuticalpollutionoftheworldsrivers AT kingac pharmaceuticalpollutionoftheworldsrivers AT jiangjj pharmaceuticalpollutionoftheworldsrivers AT kariukir pharmaceuticalpollutionoftheworldsrivers AT tumbom pharmaceuticalpollutionoftheworldsrivers AT tezelu pharmaceuticalpollutionoftheworldsrivers AT onaytt pharmaceuticalpollutionoftheworldsrivers AT lejjujb pharmaceuticalpollutionoftheworldsrivers AT vystavnay pharmaceuticalpollutionoftheworldsrivers AT vergelesy pharmaceuticalpollutionoftheworldsrivers AT heinzenh pharmaceuticalpollutionoftheworldsrivers AT perezparadaa pharmaceuticalpollutionoftheworldsrivers AT simsdb pharmaceuticalpollutionoftheworldsrivers AT figym pharmaceuticalpollutionoftheworldsrivers AT goodd pharmaceuticalpollutionoftheworldsrivers AT tetac pharmaceuticalpollutionoftheworldsrivers |