Genetic susceptibility to infectious disease in East African Shorthorn Zebu: A genome-wide analysis of the effect of heterozygosity and exotic introgression

Positive multi-locus heterozygosity-fitness correlations have been observed in a number of natural populations. They have been explained by the correlation between heterozygosity and inbreeding, and the negative effect of inbreeding on fitness (inbreeding depression). Exotic introgression in a local...

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Bibliographic Details

Main Authors:	Murray, Gemma G.R., Woolhouse, Mark E.J., Tapio, Miika, Mbole-Kariuki, Mary N., Sonstegard, Tad S., Thumbi, Samuel M., Jennings, Amy E., Wyk, Ilana Conradie van, Chase-Topping, Margo, Kiara, Henry K., Toye, Philip G., Coetzer, Koos, Bronsvoort, Barend M. de C., Hanotte, Olivier H.
Format:	Journal Article
Language:	Inglés
Published:	Springer 2013
Subjects:	animal diseases genomes genetics zebu infectious diseases animal breeding
Online Access:	https://hdl.handle.net/10568/116126