Salmonella identified in pigs in Kenya and Malawi reveals the potential for zoonotic transmission in emerging pork markets
Salmonella is a major cause of foodborne disease globally. Pigs can carry and shed non-typhoidal Salmonella (NTS) asymptomatically, representing a significant reservoir for these pathogens. To investigate Salmonella carriage by African domestic pigs, faecal and mesenteric lymph node samples were tak...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Journal Article |
| Language: | Inglés |
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Public Library of Science
2020
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10568/110336 |
| _version_ | 1855534753371914240 |
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| author | Wilson, C.N. Pulford, C.V. Akoko, James M. Sepulveda, B.P. Predeus, A.V. Bevington, J. Duncan, P. Hall, N. Wigley, P. Feasey, N. Pinchbeck, G. Hinton, J.C.D. Gordon, M.A. Fèvre, Eric M. |
| author_browse | Akoko, James M. Bevington, J. Duncan, P. Feasey, N. Fèvre, Eric M. Gordon, M.A. Hall, N. Hinton, J.C.D. Pinchbeck, G. Predeus, A.V. Pulford, C.V. Sepulveda, B.P. Wigley, P. Wilson, C.N. |
| author_facet | Wilson, C.N. Pulford, C.V. Akoko, James M. Sepulveda, B.P. Predeus, A.V. Bevington, J. Duncan, P. Hall, N. Wigley, P. Feasey, N. Pinchbeck, G. Hinton, J.C.D. Gordon, M.A. Fèvre, Eric M. |
| author_sort | Wilson, C.N. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Salmonella is a major cause of foodborne disease globally. Pigs can carry and shed non-typhoidal Salmonella (NTS) asymptomatically, representing a significant reservoir for these pathogens. To investigate Salmonella carriage by African domestic pigs, faecal and mesenteric lymph node samples were taken at slaughter in Nairobi, Busia (Kenya) and Chikwawa (Malawi) between October 2016 and May 2017. Selective culture, antisera testing and whole genome sequencing were performed on samples from 647 pigs; the prevalence of NTS carriage was 12.7% in Busia, 9.1% in Nairobi and 24.6% in Chikwawa. Two isolates of S. Typhimurium ST313 were isolated, but were more closely related to ST313 isolates associated with gastroenteritis in the UK than bloodstream infection in Africa. The discovery of porcine NTS carriage in Kenya and Malawi reveals potential for zoonotic transmission of diarrhoeal strains to humans in these countries, but not for transmission of clades specifically associated with invasive NTS disease in Africa. |
| format | Journal Article |
| id | CGSpace110336 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2020 |
| publishDateRange | 2020 |
| publishDateSort | 2020 |
| publisher | Public Library of Science |
| publisherStr | Public Library of Science |
| record_format | dspace |
| spelling | CGSpace1103362025-12-08T09:54:28Z Salmonella identified in pigs in Kenya and Malawi reveals the potential for zoonotic transmission in emerging pork markets Wilson, C.N. Pulford, C.V. Akoko, James M. Sepulveda, B.P. Predeus, A.V. Bevington, J. Duncan, P. Hall, N. Wigley, P. Feasey, N. Pinchbeck, G. Hinton, J.C.D. Gordon, M.A. Fèvre, Eric M. swine zoonoses foodborne diseases salmonella health microbiological analysis genomes Salmonella is a major cause of foodborne disease globally. Pigs can carry and shed non-typhoidal Salmonella (NTS) asymptomatically, representing a significant reservoir for these pathogens. To investigate Salmonella carriage by African domestic pigs, faecal and mesenteric lymph node samples were taken at slaughter in Nairobi, Busia (Kenya) and Chikwawa (Malawi) between October 2016 and May 2017. Selective culture, antisera testing and whole genome sequencing were performed on samples from 647 pigs; the prevalence of NTS carriage was 12.7% in Busia, 9.1% in Nairobi and 24.6% in Chikwawa. Two isolates of S. Typhimurium ST313 were isolated, but were more closely related to ST313 isolates associated with gastroenteritis in the UK than bloodstream infection in Africa. The discovery of porcine NTS carriage in Kenya and Malawi reveals potential for zoonotic transmission of diarrhoeal strains to humans in these countries, but not for transmission of clades specifically associated with invasive NTS disease in Africa. 2020-11-24 2020-11-28T15:26:41Z 2020-11-28T15:26:41Z Journal Article https://hdl.handle.net/10568/110336 en Open Access Public Library of Science Wilson, C.N., Pulford, C.V., Akoko, J., Sepulveda, B.P., Predeus, A.V., Bevington, J., Duncan, P., Hall, N., Wigley, P., Feasey, N., Pinchbeck, G., Hinton, J.C.D., Gordon, M.A. and Fèvre, E.M. 2020. Salmonella identified in pigs in Kenya and Malawi reveals the potential for zoonotic transmission in emerging pork markets. PLOS Neglected Tropical Diseases 14(11): e0008796. |
| spellingShingle | swine zoonoses foodborne diseases salmonella health microbiological analysis genomes Wilson, C.N. Pulford, C.V. Akoko, James M. Sepulveda, B.P. Predeus, A.V. Bevington, J. Duncan, P. Hall, N. Wigley, P. Feasey, N. Pinchbeck, G. Hinton, J.C.D. Gordon, M.A. Fèvre, Eric M. Salmonella identified in pigs in Kenya and Malawi reveals the potential for zoonotic transmission in emerging pork markets |
| title | Salmonella identified in pigs in Kenya and Malawi reveals the potential for zoonotic transmission in emerging pork markets |
| title_full | Salmonella identified in pigs in Kenya and Malawi reveals the potential for zoonotic transmission in emerging pork markets |
| title_fullStr | Salmonella identified in pigs in Kenya and Malawi reveals the potential for zoonotic transmission in emerging pork markets |
| title_full_unstemmed | Salmonella identified in pigs in Kenya and Malawi reveals the potential for zoonotic transmission in emerging pork markets |
| title_short | Salmonella identified in pigs in Kenya and Malawi reveals the potential for zoonotic transmission in emerging pork markets |
| title_sort | salmonella identified in pigs in kenya and malawi reveals the potential for zoonotic transmission in emerging pork markets |
| topic | swine zoonoses foodborne diseases salmonella health microbiological analysis genomes |
| url | https://hdl.handle.net/10568/110336 |
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