Iron absorption from iron-biofortified sweetpotato is higher than regular sweetpotato in Malawian women while iron absorption from regular and iron-biofortified potatoes is high in Peruvian women
Background: Sweetpotato and potato are fast-maturing staple crops and widely consumed in low- and middle-income countries. Conventional breeding to biofortify these crops with iron could improve iron intakes. To our knowledge, iron absorption from sweetpotato and potato has not been assessed. Object...
| Autores principales: | , , , , , , , , , , , , , , |
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| Formato: | Journal Article |
| Lenguaje: | Inglés |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://hdl.handle.net/10568/110193 |
| _version_ | 1855525802331865088 |
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| author | Jongstra, R. Mwangi, M. Burgos, G. Zeder, C. Low, Jan W. Mzembe, G. Liria, R. Penny, M. Andrade, M.I. Fairweather-Tait, S. Felde, T. zum Campos, Hugo Phiri, K.S. Zimmermann, M. Wegmüller, R. |
| author_browse | Andrade, M.I. Burgos, G. Campos, Hugo Fairweather-Tait, S. Felde, T. zum Jongstra, R. Liria, R. Low, Jan W. Mwangi, M. Mzembe, G. Penny, M. Phiri, K.S. Wegmüller, R. Zeder, C. Zimmermann, M. |
| author_facet | Jongstra, R. Mwangi, M. Burgos, G. Zeder, C. Low, Jan W. Mzembe, G. Liria, R. Penny, M. Andrade, M.I. Fairweather-Tait, S. Felde, T. zum Campos, Hugo Phiri, K.S. Zimmermann, M. Wegmüller, R. |
| author_sort | Jongstra, R. |
| collection | Repository of Agricultural Research Outputs (CGSpace) |
| description | Background: Sweetpotato and potato are fast-maturing staple crops and widely consumed in low- and middle-income countries. Conventional breeding to biofortify these crops with iron could improve iron intakes. To our knowledge, iron absorption from sweetpotato and potato has not been assessed. Objective: The aim was to assess iron absorption from regular and iron-biofortified orange-fleshed sweetpotato in Malawi and yellow-fleshed potato and iron-biofortified purple-fleshed potato in Peru. Methods: We conducted 2 randomized, multiple-meal studies in generally healthy, iron-depleted women of reproductive age. Malawian women (n = 24) received 400 g regular or biofortified sweetpotato test meals and Peruvian women (n = 35) received 500 g regular or biofortified potato test meals. Women consumed the meals at breakfast for 2 wk and were then crossed over to the other variety. We labeled the test meals with 57Fe or 58Fe and measured cumulative erythrocyte incorporation of the labels 14 d after completion of each test-meal sequence to calculate iron absorption. Iron absorption was compared by paired-sample t tests. Results: The regular and biofortified orange-fleshed sweetpotato test meals contained 0.55 and 0.97 mg Fe/100 g. Geometric mean (95% CI) fractional iron absorption (FIA) was 5.82% (3.79%, 8.95%) and 6.02% (4.51%, 8.05%), respectively (P = 0.81), resulting in 1.9-fold higher total iron absorption (TIA) from biofortified sweetpotato (P < 0.001). The regular and biofortified potato test meals contained 0.33 and 0.69 mg Fe/100 g. FIA was 28.4% (23.5%, 34.2%) from the regular yellow-fleshed and 13.3% (10.6%, 16.6%) from the biofortified purple-fleshed potatomeals, respectively (P < 0.001), resulting in no significant difference in TIA (P = 0.88). Conclusions: FIA from regular yellow-fleshed potato was remarkably high, at 28%. Iron absorbed from both potato test meals covered 33% of the daily absorbed iron requirement for women of reproductive age, while the biofortified orange-fleshed sweetpotato test meal covered 18%of this requirement. High polyphenol concentrations were likely the major inhibitors of iron absorption. |
| format | Journal Article |
| id | CGSpace110193 |
| institution | CGIAR Consortium |
| language | Inglés |
| publishDate | 2020 |
| publishDateRange | 2020 |
| publishDateSort | 2020 |
| publisher | Elsevier |
| publisherStr | Elsevier |
| record_format | dspace |
| spelling | CGSpace1101932025-11-29T05:22:16Z Iron absorption from iron-biofortified sweetpotato is higher than regular sweetpotato in Malawian women while iron absorption from regular and iron-biofortified potatoes is high in Peruvian women Jongstra, R. Mwangi, M. Burgos, G. Zeder, C. Low, Jan W. Mzembe, G. Liria, R. Penny, M. Andrade, M.I. Fairweather-Tait, S. Felde, T. zum Campos, Hugo Phiri, K.S. Zimmermann, M. Wegmüller, R. iron potatoes sweet potatoes biofortification gender Background: Sweetpotato and potato are fast-maturing staple crops and widely consumed in low- and middle-income countries. Conventional breeding to biofortify these crops with iron could improve iron intakes. To our knowledge, iron absorption from sweetpotato and potato has not been assessed. Objective: The aim was to assess iron absorption from regular and iron-biofortified orange-fleshed sweetpotato in Malawi and yellow-fleshed potato and iron-biofortified purple-fleshed potato in Peru. Methods: We conducted 2 randomized, multiple-meal studies in generally healthy, iron-depleted women of reproductive age. Malawian women (n = 24) received 400 g regular or biofortified sweetpotato test meals and Peruvian women (n = 35) received 500 g regular or biofortified potato test meals. Women consumed the meals at breakfast for 2 wk and were then crossed over to the other variety. We labeled the test meals with 57Fe or 58Fe and measured cumulative erythrocyte incorporation of the labels 14 d after completion of each test-meal sequence to calculate iron absorption. Iron absorption was compared by paired-sample t tests. Results: The regular and biofortified orange-fleshed sweetpotato test meals contained 0.55 and 0.97 mg Fe/100 g. Geometric mean (95% CI) fractional iron absorption (FIA) was 5.82% (3.79%, 8.95%) and 6.02% (4.51%, 8.05%), respectively (P = 0.81), resulting in 1.9-fold higher total iron absorption (TIA) from biofortified sweetpotato (P < 0.001). The regular and biofortified potato test meals contained 0.33 and 0.69 mg Fe/100 g. FIA was 28.4% (23.5%, 34.2%) from the regular yellow-fleshed and 13.3% (10.6%, 16.6%) from the biofortified purple-fleshed potatomeals, respectively (P < 0.001), resulting in no significant difference in TIA (P = 0.88). Conclusions: FIA from regular yellow-fleshed potato was remarkably high, at 28%. Iron absorbed from both potato test meals covered 33% of the daily absorbed iron requirement for women of reproductive age, while the biofortified orange-fleshed sweetpotato test meal covered 18%of this requirement. High polyphenol concentrations were likely the major inhibitors of iron absorption. 2020-12 2020-11-16T15:47:58Z 2020-11-16T15:47:58Z Journal Article https://hdl.handle.net/10568/110193 en Open Access Elsevier Jongstra, R., Mwangi, M., Burgos, G., Zeder, C., Low, J.W., Mzembe, G., Liria, R., Penny, M., Andrade, M.I., Fairweather-Tait, S., Felde, T. zum, Campos, H., Phiri, K.S., Zimmermann, M., Wegmüller, R. (2020). Iron absorption from iron-biofortified sweetpotato is higher than regular sweetpotato in Malawian women while iron absorption from regular and iron-biofortified potatoes is high in Peruvian women. Journal of Nutrition. ISSN 1541-6100. Published online 13Nov2020. |
| spellingShingle | iron potatoes sweet potatoes biofortification gender Jongstra, R. Mwangi, M. Burgos, G. Zeder, C. Low, Jan W. Mzembe, G. Liria, R. Penny, M. Andrade, M.I. Fairweather-Tait, S. Felde, T. zum Campos, Hugo Phiri, K.S. Zimmermann, M. Wegmüller, R. Iron absorption from iron-biofortified sweetpotato is higher than regular sweetpotato in Malawian women while iron absorption from regular and iron-biofortified potatoes is high in Peruvian women |
| title | Iron absorption from iron-biofortified sweetpotato is higher than regular sweetpotato in Malawian women while iron absorption from regular and iron-biofortified potatoes is high in Peruvian women |
| title_full | Iron absorption from iron-biofortified sweetpotato is higher than regular sweetpotato in Malawian women while iron absorption from regular and iron-biofortified potatoes is high in Peruvian women |
| title_fullStr | Iron absorption from iron-biofortified sweetpotato is higher than regular sweetpotato in Malawian women while iron absorption from regular and iron-biofortified potatoes is high in Peruvian women |
| title_full_unstemmed | Iron absorption from iron-biofortified sweetpotato is higher than regular sweetpotato in Malawian women while iron absorption from regular and iron-biofortified potatoes is high in Peruvian women |
| title_short | Iron absorption from iron-biofortified sweetpotato is higher than regular sweetpotato in Malawian women while iron absorption from regular and iron-biofortified potatoes is high in Peruvian women |
| title_sort | iron absorption from iron biofortified sweetpotato is higher than regular sweetpotato in malawian women while iron absorption from regular and iron biofortified potatoes is high in peruvian women |
| topic | iron potatoes sweet potatoes biofortification gender |
| url | https://hdl.handle.net/10568/110193 |
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